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MDS (myelodysplastic syndromes) and Inflammation

Interview with Dr. Alan List from the H. Lee Moffitt Cancer Center and Research Institute - Recorded March 2016
Questions answered include:

  1. What is inflammation?
  2. What are some examples of inflammatory responses produced by the body?
  3. What is the difference between an innate immune response and adaptive immunity?
  4. What are myeloid derived suppressor cells (MDSCs)? And what is their role in the bone marrow?
  5. Do they drive the emergence of the MDS clone?
  6. What drives the expansion of these cells?
  7. What is pyroptosis?
  8. What are common inflammatory symptoms in patients with MDS?
  9. How can the MDS clone be targeted specifically therapeutically?
  10. What advice can be given to patients with MDS that experience inflammatory disorders?
  11. What does this mean for patient care and treatments in the future?
  12. What is the direction for future research?