The standard way to diagnose PNH is by flow cytometry analysis of circulating red blood cells or granulocytes (a type of white blood cell) from a blood sample. The same test, if abnormal, can tell us something about the cause of bone marrow failure in some patients with aplastic anemia. A different type of flow cytometry test, typically done on bone marrow, can give some indication whether such patients are tending towards myelodysplasia instead.
Dr. David Araten (New York University) discusses the importance of flow cytometry in relation to PNH and aplastic anemia. He also talks about the latest research in flow cytometry in patients and other research that is currently on the horizon.
By the end of this program, you will understand:
- What is on the horizon with flow cytometry and PNH
- The importance of being tested for the PNH clone
- What is means if the flow cytometry test is abnormal
- A bit about the technology behind flow cytometry