Keynote: Past, Present, Future of Transporters
In the ten years since the first AAPS Transporter Workshop was co-chaired by myself and Rajesh Krishna in Peachtree, Georgia, the field of transporters has grown exponentially and has transformed the world of ADME to ADMET, where T stands for transport! In Peachtree, the agenda for the transporter workshop was mostly confined to P-gp and BCRP with only a smattering of understanding of OATPs, OATs and other transporters in the ADMET of drugs. In 2020, we now have a clearer understanding of the transporters important in ADMET of drugs. Its an exciting time to be a researcher in the field of transporter. This presentation will review where we have been, where we are and where we are going in the field of transporters.
Hot Topic: Enabling transporter-DDI risk assessment pre-FIH/P
Session description unavailable.
Chalk Talk: The Transporter CROnicles: Practical Considerations for your Studies
During this talk, the presenter is going to discuss the usual questions asked while conducting transporter studies.
- Timing of transporter studies
- GIGO – care to be taken while conducting the studies
- Applicability of in-vitro dissolution and absorption system
In the ten years since the first AAPS Transporter Workshop was co-chaired by myself and Rajesh Krishna in Peachtree, Georgia, the field of transporters has grown exponentially and has transformed the world of ADME to ADMET, where T stands for transport! In Peachtree, the agenda for the transporter workshop was mostly confined to P-gp and BCRP with only a smattering of understanding of OATPs, OATs and other transporters in the ADMET of drugs. In 2020, we now have a clearer understanding of the transporters important in ADMET of drugs. Its an exciting time to be a researcher in the field of transporter. This presentation will review where we have been, where we are and where we are going in the field of transporters.
Hot Topic: Enabling transporter-DDI risk assessment pre-FIH/P
Session description unavailable.
Chalk Talk: The Transporter CROnicles: Practical Considerations for your Studies
During this talk, the presenter is going to discuss the usual questions asked while conducting transporter studies.
- Timing of transporter studies
- GIGO – care to be taken while conducting the studies
- Applicability of in-vitro dissolution and absorption system