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Lecture 7: Fundamentals and Applications of USP 3 -the Reciprocating Cylinder Apparatus

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Learning Objectives:
  • Identify the components of USP Apparatus 3 – Reciprocating Cylinder
  • Describe the principles of operation of the apparatus
  • Summarize the biorelevance of the in vitro apparatus to in vivo conditions in the GI tract
  • Describe how to preform periodic qualification of the apparatus to ensure its optimum performance
  • Describe several applications of the USP Apparatus 3 for testing established and novel dosage forms