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Lipid NanoParticles (LNPs): Product Development for Optimal Delivery of RNA molecules

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Contributors

  • Rahul Keswani, Ph.D.

    Dr. Rahul K Keswani is a Group Leader, Formulation and Process Development at Exelead, Inc. His broad research and career interests lie in the field of systemic therapy via formulation of nanomedicinal and smart therapeutics. He is currently working with academic and industrial partners to develop and commercialize various lipid-based drug delivery systems, particularly toward optimized delivery of antibiotics as well as targeted delivery of oncological therapeutics (olignonucleotides, proteins/peptides).

    Dr. Keswani has been trained in formulation sciences through multiple academic stints, the latest being a Senior Research Fellowship in the Department of Pharmaceutical Sciences, College of Pharmacy, housed within the University of Michigan Health System at Ann Arbor, MI. As part of the Macrophage-targeted Drug Development Team under the mentorship of Dr. Gus Rosania, he published heavily on the biocrystallization and macrophage-mediated transformation of clofazimine in the human body with potential implications in targeting and controlled release of therapeutics and theranostics. He was partly funded via MICHR (Michigan Institute for Clinical & Health Research)

    Earlier, he received his MS and PhD in Chemical and Biomolecular Engineering from the University of Illinois, Urbana-Champaign and B. Tech. in Chemical Engineering from the Indian Institute of Technology Bombay. His graduate research was on the development and sub-cellular characterization of novel gene therapy vectors combining the superlative efficiency of retroviruses with the flexible capabilities of polymers and lipids to create a superior hybrid design. His graduate research mentor was Prof. Daniel W. Pack, currently the Ashland, Inc Chair at the University of Kentucky.

June 25, 2020
Thu 12:30 PM EDT

Duration 1H 30M

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