This symposium focuses on challenges and innovations in epilepsy treatment. While epilepsy surgery for refractory epilepsy continues to be underutilized, minimally invasive techniques for localizing and treating focal epilepsy are making epilepsy surgery more attractive to patients due to their relative safety and tolerability in terms of discomfort and length of hospital stay. Genetic testing in adults with seizures can aid in the diagnosis and treatment of focal epilepsy. The specific sequence and duration of treatment for immune-related epilepsy is rarely discussed in detail, particularly in association with the causative antibody. Although there is abundant literature on this topic, healthcare providers are still seeking more detailed guidance on the treatment approaches of this difficult clinical entity. Finally, the initial and second choice of AEDs remains complex.
Following participation in this activity, learners should be able to:
- Discuss all technical approaches, inclusive of minimally invasive tools (stereo-EEG, standard depth electrodes, subdural grids and strips, mapping for eloquent cortex with each technique, cortical resection, stereo-EEG thermos-ablation, laser ablation and responsive neurostimulator placement), and delineate the limitations and advantages of each
- Formulate a possible epilepsy surgical plan that incorporates all technical approaches including the aforementioned minimally invasive tools
- Appropriately select focal epilepsy patients for genetic testing; describe how to prioritize and select the genetic test(s) and develop treatment strategies implicated by the genetic results
- Formulate a treatment sequence for immune-related epilepsies, depending on response, with incorporation of the duration of each treatment course, according to the best available information
- Identify the AEDs to be used earlier in the course of treatment based on effectiveness, side effect profile, and cost
Neurologists, epileptologists, nurse practitioners, physician assistants, nurses, pharmacists
Co-chairs: Cynthia Harden, M.D. and Jerry Shih, M.D.
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