Description
Presented at the 2018 AO Annual Meeting
March 11, 2017
Blood-derived materials have been used as the regenerative agents of oral structures. These blood related products include but are not limited to blood clots, platelet rich plasma (PRP), platelet rich fibrin gel (PRFG), Leukocyte enriched platelet rich fibrin
(L PRF) or advanced platelet rich fibrin (A-PRF) etc). The regenerative capacity of blood-derived materials is largely attributed to its composition, including many different growth factors and cytokines. This presentation highlights the ingredients of these materials and the differences among them and presents current evidence and understanding related to these materials for hard and soft tissue reconstruction in the oral cavity.
Objectives: Upon completion of this presentation, participants should be able to: 1) compare the main differences among blood products; 2) list the protocol on how to produce these blood products; and 3) indicate when these blood products can be used to promote soft and hard tissue regeneration in the oral cavity.
Contributors
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Hom-Lay Wang, DDS, MSD, PhD
Hom-Lay Wang, DDS., MSD., Ph D, Professor and Director of Graduate Periodontics at the University of Michigan. Dr. Wang received his DDS from Taipei Medical College, Taipei, Taiwan, DDS, MSD from Case Western Reserve University, Cleveland, Ohio and Ph D from Hiroshima University, Japan. He has co-editor two textbooks, published more than 50 book chapters/invited reviews and more than 600 scientific articles. Dr. Wang currently serves as a member of Task Force as Future Science Strategy for the American Academy of Periodontology (AAP), Nevins Teaching and Clinical Research Fellowship Selection Committee (AAPF), Secretary of the Academy of Osseointegration (AO). Dr. Wang is a Diplomate and a Former Chair and Director of the American Board of Periodontology, a Fellow of American College of Dentists as well as a Fellow and a Former Board of Director of AO, a Diplomate and Former President and Board Director of the ICOI, former President of Midwest Society of Periodontology, former Consultant for the ADA Commission on Dental Accreditation and many others. He serves as an Associate Editor for The International Journal of Oral & Maxillofacial Implants, Periodontology, International Journal of Oral Implantology, Oral Surgery, Esthetic & Implant Dentistry Organization, eJournal of Oral & Maxillofacial Research, and Founding Editorial board member for Clinical Advances in Periodontics, Editorial Board member for the JP, JCP, COIR, IJOMI, IJPRD and many others. Dr. Wang is the recipient of many awards/honors including but are not limited to: AADS clinical research fellowship award (1992), Best Faculty Award (2003), The Charles E. English Annual Award in Clinical Science and Techniques (2004), Best papers in Journal of Oral Implantology (2004) and Implant Dentistry (2004), Morton L. Perel Annual Award for Dental Implant Educator (2007), AAP University of Michigan Outstanding Teaching and Mentoring in Periodontics (2010), ITI Andre Schroeder Research Prize (2014), AO Osseointegration Foundation Clinical Research Recipient (2016), AAP Outstanding Educator Award (2017), AAP Distinguished Scientist Award (2017), ADEA William J. Gies Annual Periodontology Award (2018), University of Michigan Distinguished Faculty Research Mentoring Award (2019) and AAP Master Clinician Award (2019).
BioHorizons, Zimmer Dental, Osteogenic Biomaterials, NeoBiotech, Straumann, Biomet3i, Dentium