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Description
Current treatment modalities to restore oral tissues and teeth provide functional and structural restoration of the compromised or lost tissues; yet, many of these approaches do not meet the need for more biologic and physiologic treatment outcomes. The emergence of tissue engineering and regenerative medicine over the past 25 years has been a gateway to new paradigms of treatment in dentistry, particularly for periodontal, peri-implant, and alveolar bone regeneration. Historically, the use of different biomaterials and grafting agents has established a strong platform for the development of therapeutic concepts toward achieving “true“ tissue regeneration. More recently, the use of biologic agents and the advent of cell therapies has enabled an even greater capacity to achieve regeneration in more complex and compromised clinical scenarios. This course will provide an overview of the evolution of stem cell therapeutic approaches in dentistry and highlight current applications for periodontal, peri-implant, and alveolar bone regeneration using stem cells. Key regenerative principles will be discussed and clinical cases will be presented demonstrating how these strategies can be implemented in clinical practice.
Upon completion of this presentation, participants should be able to: 1) explain the scientific and clinical rationale for stem cell therapy for oral tissue regeneration; 2) identify clinical applications for stem cell therapy approaches for regeneration of periodontal, peri-implant, and alveolar bone tissues; and 3) discuss the key parameters for the advancement of stem cell therapies into clinical practice.