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Description

Learning Objectives

• Review the mechanisms leading to false-positive HIV test results in patients undergoing novel therapies.
• Describe the impact of COVID-19 on HIV diagnostic accuracy.
• Identify best practices for interpretation and communication of complex HIV test results in the context of emerging therapies and infectious diseases.

Articles

• Villalba JA, Maus MV, et al. 2022. False-Positive Human Immunodeficiency Virus Test Results in Patients Receiving Lentivirus-Based Chimeric Antigen Receptor T-Cell Therapy: Case Report, Review of the Literature, and Proposed Recommendations. The Journal of Infectious Diseases 225:1933–1936.
• Gudipati S, Shallal A, et al. 2023. Increase in False-Positive Fourth-Generation Human Immunodeficiency Virus Tests in Patients With Coronavirus Disease 2019. Clinical Infectious Diseases 77:615–619.

Presenters

• Jonathan Wilcock, D.O., Hematopathology Fellow, University of Virginia.
• Marisa Nielsen, Ph.D., D(ABMM), SM(ASCP)CM, Assistant Director for Clinical Microbiology, Boston Medical Center.

Moderator

• Emily Snavely, Ph.D., D(ABMM), Associate Director of Clinical Microbiology, Assistant Professor of Pathology, University of Virginia Health System.

Discussion Panel

• Benjamin Pinsky, M.D., Ph.D., Director of the Clinical Virology Laboratory, Stanford Health Care and Stanford Children's Hospital.
• Patrick Jackson, M.D., Assistant Professor of Infectious Disease and International Health, University of Virginia.