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Carcinoma of Unknown Primary: Diagnostic Approaches for Radiologists


Carcinoma of Unknown Primary: Diagnostic Approaches for Radiologists

Description & Learning Objectives
Carcinoma of unknown primary is an important and complex disease entity that presents challenges to interpreting radiologists. This article presents a comprehensive clinical, pathologic, and radiologic work-up and assessment for radiologists. It is important for the radiologist to know the p16, high-risk human papilloma virus, and Epstein-Barr virus status; nodal drainage patterns of head and neck squamous cell carcinoma; and the utility of various imaging modalities to help identify the primary site and guide therapy.

Upon completion of this activity, participants will gain strategies to understand the clinical, pathologic, and radiologic evaluation of carcinoma of unknown primary (CUP); to provide an overview of the clinical and pathologic work-up for CUP that aids in imaging interpretation; and to recognize patterns of nodal involvement for identification of the primary disease.
Instructions for Participation
To complete this activity, learners will read an article and submit a course evaluation. Once all elements are completed, a certificate will be automatically added to your transcript.
Credit Dates
Available: 5/11/2023
Expires: 5/10/2026

Planners & Faculty
ASNR would like to thank the following individuals for reviewing this article.
Joshua Nickerson, Editor in Chief
Robert Quencer, Consulting Editor
Toshio Moritani, Associate Editor
Meng Law, Associate Editor
Edward Escott, Associate Editor
Levi Chazen, Associate Editor
Scott Faro, Associate Editor
Susan Palasis, Associate Editor
Katyucia de Macedo Rodriguez, Associate Editor

Accreditation Statement
The American Society of Neuroradiology is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

The American Society of Neuroradiology designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Disclosure
In compliance with ACCME requirements and guidelines, ASNR has developed a policy for disclosure and review of potential conflicts of interest and a method for resolution if a conflict does exist. ASNR maintains a tradition of scientific integrity and objectivity in its educational activities. In order to preserve these values and ensure its educational activities are independent and free of commercial bias, all individuals, including planners, presenters, moderators and evaluators, participating in an ASNR educational activity, or an activity jointly provided by ASNR must disclose all relevant financial relationships with ineligible companies, as defined by the ACCME. Unless listed below, all planners and individuals in control of content have nothing to disclose.

Authors have no disclosures.

Meng Law: Stockholder, Clinical Imaging
Edward Escott: Grant, Atherysys, Inc.; Royalties, Thieme Medical Publishers
Levi Chazen: Grant, Athersys; Stock Ownership or Private Investments: Amgen, Catalent, Charles River Labs, Intuitive Surgical, Stryker, United Health Group
Scott Faro: Royalties, Springer Publications