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The Big Brain Theory: A Review of Overgrowth Syndromes for the Neuroradiologist

The Big Brain Theory: A Review of Overgrowth Syndromes for the Neuroradiologist

Description & Learning Objectives
Overgrowth syndromes are a generally rare and diverse spectrum of disease states related to genetic mutations regulating cell growth and metabolism, resulting in pathologic overgrowth of anatomic structures. Due to their rarity, radiologists may be generally unfamiliar with these diseases. Furthermore, the complexity of these conditions may pose a challenge to clinicians seeking to understand these syndromes. In this review, we provide an overview of the common imaging findings of overgrowth syndromes for the neuroradiologist with an additional emphasis on predisposition to malignancy. Understanding the most common neuroimaging findings and considerations associated with overgrowth syndromes helps to provide the highest quality of care to these patients by equipping the radiologist with the skills to actively search for characteristic disease manifestations and complications.

Upon completion of this activity, participants will gain strategies to identify the neuroimaging findings in overgrowth syndromes.
Instructions for Participation
To complete this activity, learners will read an article and submit a course evaluation. Once all elements are completed, a certificate will be automatically added to your transcript.
Credit Dates
Available: 1/1/2024
Expires: 12/31/2027

Planners & Faculty
ASNR would like to thank the following individuals for reviewing this article.
Joshua Nickerson, Editor in Chief
Ashok Srinivasan, Associate Editor
Allison Grayev, Associate Editor
Edward Escott, Associate Editor
Mesha Martinez, Associate Editor
Scott Faro, Associate Editor
Susan Palasis, Associate Editor

Accreditation Statement
The American Society of Neuroradiology is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

The American Society of Neuroradiology designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

In compliance with ACCME requirements and guidelines, ASNR has developed a policy for disclosure and review of potential conflicts of interest and a method for resolution if a conflict does exist. ASNR maintains a tradition of scientific integrity and objectivity in its educational activities. In order to preserve these values and ensure its educational activities are independent and free of commercial bias, all individuals, including planners, presenters, moderators and evaluators, participating in an ASNR educational activity, or an activity jointly provided by ASNR must disclose all relevant financial relationships with ineligible companies, as defined by the ACCME. Unless listed below, all planners and individuals in control of content have nothing to disclose.

All authors have no disclosures.

Edward Escott: Grant, Atherysys, Inc.; Royalties, Thieme Medical Publishers
Scott Faro: Royalties, Springer Publications