2021 IADR/AADR/CADR General Session
The 99th General Session & Exhibition of the IADR was to be held in conjunction with the 50th Annual Meeting of the American Association for Dental Research and the 45th Annual Meeting of the Canadian Association for Dental Research, from July 21-24, 2021 as a Virtual Experience.The recordings in this library from the meeting are a selection of the science that was to be presented as part of the General Session. These recordings give you the opportunity to participate in the meeting and hear from leading researchers. The recordings include IADR Distinguished Lecture Series speakers, the IADR Academy and symposia from a collection of scientific groups and networks.
This session can be purchased as part of the full meeting recordings within the product bundles
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Session Description
Organ-on-a-Chip systems combined with Stem Cell Biology is creating a paradigm shift in the understanding of cell-cell, cell-matrix, host-microbiome, and host-environment interactions that have immense applications in basic research and drug discovery.
Organ-on-a-chip systems leverage on recent advances in microfluidic and microfabrication technologies to create miniaturized devices containing hollow microchannels and microchambers that support the continuous supply of nutrients and drainage of metabolic wastes, application of shear stress, and model micro/nano features. These systems also enable the application of test substances (oral-care products and biomaterials) in a close to clinical use context.
These features of microfluidic organ-on-chip systems have enabled the reconstruction of the native physiology of human tissues and the complex interactions between cells, matrix, microbiome and/or external environment. This has led to an exponential increase in the application of organ-on-chip systems across various organ systems in the body. In the last 5 years, these next-generation tools have gained traction in dental and craniofacial research. Some examples include skin-on-chip, tooth-on-chip, oral mucosa-on-chip, salivary tissue-on-chip and bone-on-chip. This symposium aims to present the applications of these next-generation microfluidic and organ-on-chip technologies in dental and craniofacial research.
Learning Objectives
July 21, 2021
Presenters
Danielle Benoit - Development of a Functional Salivary Gland Tissue Chip With Potential for Drug Screening
Cristiane França - Applications of Tooth-on-a-Chip for Safety and Biocompatibility Assessment of Dental Materials
Gopu Sriram - Applications of Organ-on-a-Chip Systems for Skin and Oral Mucosa Reconstruction
Stella Alimperti - 3D Printed Oral Microfluidic Platforms
Sponsoring Groups/Networks
Craniofacial Biology Research, Pulp Biology & Regeneration Research, Stem Cell Biology Research
CE Credits
1.5 Contact Hours
Financial Interest Disclosure:
NONE
Organ-on-a-Chip systems combined with Stem Cell Biology is creating a paradigm shift in the understanding of cell-cell, cell-matrix, host-microbiome, and host-environment interactions that have immense applications in basic research and drug discovery.
Organ-on-a-chip systems leverage on recent advances in microfluidic and microfabrication technologies to create miniaturized devices containing hollow microchannels and microchambers that support the continuous supply of nutrients and drainage of metabolic wastes, application of shear stress, and model micro/nano features. These systems also enable the application of test substances (oral-care products and biomaterials) in a close to clinical use context.
These features of microfluidic organ-on-chip systems have enabled the reconstruction of the native physiology of human tissues and the complex interactions between cells, matrix, microbiome and/or external environment. This has led to an exponential increase in the application of organ-on-chip systems across various organ systems in the body. In the last 5 years, these next-generation tools have gained traction in dental and craniofacial research. Some examples include skin-on-chip, tooth-on-chip, oral mucosa-on-chip, salivary tissue-on-chip and bone-on-chip. This symposium aims to present the applications of these next-generation microfluidic and organ-on-chip technologies in dental and craniofacial research.
Learning Objectives
- Educate the wider dental community on ‘what are organ-on-chip systems, their potential and opportunities in dental and craniofacial research?'
- Highlight the value addition and capabilities of these next-generation tools over conventional cultures systems.
- Discuss the recent applications of the microfluidic and organ-on-chip technologies in dental and craniofacial research.
- Illustrate the developments through their applications in the skin, salivary gland, pulp/dentin, oral mucosal, and bone biology,
- Illustrate their applications in the assessment of safety, toxicity, biocompatibility, and drug absorption of dental/oral-care products.
July 21, 2021
Presenters
Danielle Benoit - Development of a Functional Salivary Gland Tissue Chip With Potential for Drug Screening
Cristiane França - Applications of Tooth-on-a-Chip for Safety and Biocompatibility Assessment of Dental Materials
Gopu Sriram - Applications of Organ-on-a-Chip Systems for Skin and Oral Mucosa Reconstruction
Stella Alimperti - 3D Printed Oral Microfluidic Platforms
Sponsoring Groups/Networks
Craniofacial Biology Research, Pulp Biology & Regeneration Research, Stem Cell Biology Research
CE Credits
1.5 Contact Hours
NONE
Not eligible for individual purchase must purchase as part of a meeting bundle.
