2021 IADR/AADR/CADR General Session
The 99th General Session & Exhibition of the IADR was to be held in conjunction with the 50th Annual Meeting of the American Association for Dental Research and the 45th Annual Meeting of the Canadian Association for Dental Research, from July 21-24, 2021 as a Virtual Experience.The recordings in this library from the meeting are a selection of the science that was to be presented as part of the General Session. These recordings give you the opportunity to participate in the meeting and hear from leading researchers. The recordings include IADR Distinguished Lecture Series speakers, the IADR Academy and symposia from a collection of scientific groups and networks.
This session can be purchased as part of the full meeting recordings within the product bundles
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Session Description
Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) is the causative agent of Coronavirus Infectious Disease 2019 (COVID-19), the most serious pandemic in a century. COVID-19 has caused more than 1.2 million deaths worldwide with the United States (US) leading the world in total cases and deaths. COVID-19 has critically strained economies, healthcare systems, and disrupted dental clinical practice, dental education, and research across the world. Despite signs of infection, including the presence of virus in saliva, oral-specific symptoms (loss of taste), and the potential for droplet and fomite transmission from the oral cavity, the involvement of the oral cavity in COVID-19 is poorly understood. Predominant research interest has focused on the nasal-lung axis COVID-19 pathogenesis and the development of a robust immune response; points critical to the development of efficacious vaccines which are now emminently on the horizon. However, critical to understanding the physiology of COVID-19, recent reports implicate the oral cavity as a key site of infection and transmission (Warner and Byrd, et al., 2020; Medrxiv). Pinpointing oral cell-specific tropism for SARS-CoV-2, establishing cell niches supportive of viral replication, and characterizing the potential for oral cavity secretions to spread within a host (e.g., oral-lung axis) or transmit extra-orally will undoubtedly extend our understanding of this disease and until we have a SARS-CoV-2 vaccine which is widely available, it is critical to support public health strategies to reduce risk such as universal mask wearing, social distancing, and hand hygiene. Moreover, deployment of established and novel dental infection control strategies to reduce the risk transmission are now being tested. Because the professions of dental hygiene and dentistry are among the most heavily impacted by COVID-19, it is prudent for dentistry/dental research to “lean in” and to take the lead in establishing the basic biology of the oral COVID-19 disease, novel and effective risk mitigation strategies, and promote evidence-based policy initiatives to promote safe clinical practice.
Learning Objectives
July 22, 2021
Presenters
Barney Graham - Rapid Development of COVID-19 Vaccines
Anne Wyllie - SalivaDIrect: a Simplified and Flexible Platform to Enhance SARS-CoV-2 Testing Capacity
Blake Warner - The Oral Axis of COVID-19 Infection and Transmission
M.A. Haniffa - The Cellular Immune Response to COVID-19 Deciphered by Single Cell Multi-Omics Across Three UK Centres
Sponsoring Groups/Networks
Clinical and Translational Science Network, Microbiology/Immunology, Salivary Research
CE Credits
1.5 Contact Hours
Financial Interest Disclosure:
Blake Warner - NoneBarney Graham - NoneAnne Wyllie - Salary support and research funding from Pfizer, Tempus, and the National Basketball Association and consulting fees from DiaSorin
Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) is the causative agent of Coronavirus Infectious Disease 2019 (COVID-19), the most serious pandemic in a century. COVID-19 has caused more than 1.2 million deaths worldwide with the United States (US) leading the world in total cases and deaths. COVID-19 has critically strained economies, healthcare systems, and disrupted dental clinical practice, dental education, and research across the world. Despite signs of infection, including the presence of virus in saliva, oral-specific symptoms (loss of taste), and the potential for droplet and fomite transmission from the oral cavity, the involvement of the oral cavity in COVID-19 is poorly understood. Predominant research interest has focused on the nasal-lung axis COVID-19 pathogenesis and the development of a robust immune response; points critical to the development of efficacious vaccines which are now emminently on the horizon. However, critical to understanding the physiology of COVID-19, recent reports implicate the oral cavity as a key site of infection and transmission (Warner and Byrd, et al., 2020; Medrxiv). Pinpointing oral cell-specific tropism for SARS-CoV-2, establishing cell niches supportive of viral replication, and characterizing the potential for oral cavity secretions to spread within a host (e.g., oral-lung axis) or transmit extra-orally will undoubtedly extend our understanding of this disease and until we have a SARS-CoV-2 vaccine which is widely available, it is critical to support public health strategies to reduce risk such as universal mask wearing, social distancing, and hand hygiene. Moreover, deployment of established and novel dental infection control strategies to reduce the risk transmission are now being tested. Because the professions of dental hygiene and dentistry are among the most heavily impacted by COVID-19, it is prudent for dentistry/dental research to “lean in” and to take the lead in establishing the basic biology of the oral COVID-19 disease, novel and effective risk mitigation strategies, and promote evidence-based policy initiatives to promote safe clinical practice.
Learning Objectives
- Gain knowledge about the basic biology and pathogenesis of COVID-19, including the clinical development of vaccines for the prevention of COVID-19 disease.
- Discuss the pathogenesis of SARS-CoV-2 in oral cavity tissues and the relationship to reported COVID-19 symptoms.
- Critically evaluate the use of saliva in diagnosis, the role of saliva in infection transmission, and strategies to reduce risk in the dental operatory.
July 22, 2021
Presenters
Barney Graham - Rapid Development of COVID-19 Vaccines
Anne Wyllie - SalivaDIrect: a Simplified and Flexible Platform to Enhance SARS-CoV-2 Testing Capacity
Blake Warner - The Oral Axis of COVID-19 Infection and Transmission
M.A. Haniffa - The Cellular Immune Response to COVID-19 Deciphered by Single Cell Multi-Omics Across Three UK Centres
Sponsoring Groups/Networks
Clinical and Translational Science Network, Microbiology/Immunology, Salivary Research
CE Credits
1.5 Contact Hours
Blake Warner - NoneBarney Graham - NoneAnne Wyllie - Salary support and research funding from Pfizer, Tempus, and the National Basketball Association and consulting fees from DiaSorin
Not eligible for individual purchase must purchase as part of a meeting bundle.
