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Enamel Defects as Biomarkers for Exposure to Environmental Stressors

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2021 IADR/AADR/CADR General Session

The 99th General Session & Exhibition of the IADR was to be held in conjunction with the 50th Annual Meeting of the American Association for Dental Research and the 45th Annual Meeting of the Canadian Association for Dental Research, from July 21-24, 2021 as a Virtual Experience.

The recordings in this library from the meeting are a selection of the science that was to be presented as part of the General Session. These recordings give you the opportunity to participate in the meeting and hear from leading researchers. The recordings include IADR Distinguished Lecture Series speakers, the IADR Academy and symposia from a collection of scientific groups and networks.

This session can be purchased as part of the full meeting recordings within the product bundles





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Session Description 
Enamel pathologies may result from mutations of genes involved in amelogenesis, or from specific environmental conditions, factors and life habits. Over the past century the levels of environmental toxins and chemicals have increased, as have exposure to novel molecules or combination of factors that can affect enamel formation. These environmental effects, which are recorded in the mineralized enamel matrix, may result in changes to the dentition that increase the risk of dental diseases. Environmental effects on tooth formation occur in the presence of increased Endocrine Disrupting Chemicals (EDCs), stress response, and excess fluoride. Ameloblasts express steroid receptors, which may cause them to be directly susceptible to environmental effects related to stress or EDCs. This symposium will feature an international panel of experts who will highlight the effects of environmental influences on enamel formation. The purpose of this session is to highlight an emergent area of research into environmental conditions that have adverse effects on enamel formation during development.

Learning Objectives
  • To become knowledgable about the value of enamel matrix as a biologic indicator of environmental stressors.
  • To appreciate the effect of an adverse environment on tooth formation.
  • To appreciate the chemistry and molecular mechanisms of action of endocrine disruptors, stress, and fluoride on forming ameloblasts and amelogenesis.
Presentation Date
July 21, 2021

Presenters
Pamela Den Besten - The Effects of Early Life Adversity on Tooth Formation
Sylvie Babajko - Environmental Toxicants and Enamel Pathologies With a Focus on Endocrine Disrupting Chemicals
Marilia Afonso & Rabelo Buzalaf - Genetic Susceptibility to Fluorosis: What Do We Know?
James Winkler - The Effect of Phenols and Phthalates on Prenatal/Perinatal Development, Health and Tooth Formation

CE Credits
1.5 Contact Hours

Financial Interest Disclosure:
NONE


Not eligible for individual purchase must purchase as part of a meeting bundle.