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Newly Developed Models of Amelogenesis

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2022 AADOCR/CADR Annunal Meeting

The 51st Annual Meeting of the AADOCR was held in conjunction with the 46th Annual Meeting of the Canadian Association for Dental Research, from March 14-26 as a hybrid experience with 839 individuals from 18 countries attending in person in Atlanta, GA and 692 individuals from 21 countries attending virtually. 

The recordings in this library from the meeting are a selection of the science that was to be presented as part of the Annual Meeting. These recordings give you the opportunity to participate in the meeting and hear from leading researchers. The recordings include IADR Distinguished Lecture Series speakers and symposia from a collection of scientific groups and networks.

This session can be purchased as part of the full meeting recordings within the product bundles

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Session Description 
This symposium will showcase a set of newly developed models for amelogenesis created from a NIDCR-supported set of cooperative agreement projects in the last two years. This NIDCR effort to develop physiologically relevant models of amelogenesis that are robust and validated so that they can advance studies of healthy and diseased human conditions involving teeth began in Summer 2019 with four awards from RFA-DE-19-004. The four research groups will present their models, describe their plans for their characterization, and describe how these models will be useful to the scientific community. This highly collaborative project also involves close involvement with which is a public data repository that hosts biological and biophysical data on these models generated by the groups. A discussion period will follow introductory remarks and presentations to engage the audience and answer questions about the models or data resources, and to inform investigators where to obtain the animal/in vitro models and data from the respective repositories. The goal is to introduce the scientific community to these available new models for study of different stages of amelogenesis and to announce availability to the large amount of biological and biophysical data currently being conducted by these supported groups that will be collected and openly shared to all.

Learning Objectives
  • Provision of new knowledge in specific areas
  • Changes in the attitude and approach of the learner to the solution of dental problems
  • Introduction to and/or mastery of specific skills and techniques
Presentation Date
March 24, 2022

Mirali Pandya - Ameloblast Differentiation and Amelogenesis: Next-Generation Models to Define Key Mechanisms and Factors Involved in Biological Enamel Formation
Jan Hu - Development and Validation of Novel Amelogenesis Models
Ophir Klein - Enamel atlas: systems-level amelogenesis tools at multiple scales
Michael Paine - Cre Mouse Models to Study Amelogenesis

Sponsoring Groups/Networks
Mineralized Tissue

CE Credits
1.5 Hours

Financial Interest Disclosure:
National Institute of Dental and Craniofacial Research (NIDCR) - employee
Texas A&M University - employee researcher/resident
University of Michigan - employee researcher
University of California, San Francisco - employee researcher
University of Southern California - employee researcher - employee staff

Not eligible for individual purchase must purchase as part of a meeting bundle.