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2022 Presidential Symposium: From Homeostasis to Dysbiosis and Back Again

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2022 IADR/APR General Session

The 100 th General Session & Exhibition of the IADR was held in conjunction with the 5th Meeting of the Asia Pacific Region. The virtual meeting was attended by individuals from around the world. Those attending the meeting could choose from among 207 Interactive Talk sessions, seven Focused Learning Sessions, three Hands-on Workshops, five satellite symposia, 52 Symposia, one Distinguished Lecture Series and a plenary. 

The recordings in this library from the meeting are a selection of the science that was to be presented as part of the General Session. These recordings give you the opportunity to participate in the meeting and hear from leading researchers. The recordings include the IADR Distinguished Lecture Series speaker and symposia from a collection of scientific groups and networks.

This session can be purchased as part of the full meeting recordings within the product bundles





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Session Description 
The Symposium will be a research showcase in Microbiology and Immunology to highlight recent research on the multidimensional interactions between bacterial species of the subgingival polymicrobial biofilm. Other research will be presented on the important temporospatial relationship of a pathogenic consortium at the base of a periodontal pocket with disease progression and that dissemination of these pathogens may be a mechanism of exacerbating certain systemic diseases such as Alzheimer’s Disease. Finally, recent research on potential immunotherapeutic interventions to target microbial virulence factors associated with dysbiosis and to target key components of an inflammatory axis will be presented and the progress in testing of these interventions in human clinical trials will be discussed.

Learning Objectives
  • To understand how interactions between bacterial species in a polymicrobial biofilm can promote or suppress dysbiosis
  • To appreciate that inflammatory tissue destruction and loss of alveolar bone in periodontitis is primarily mediated by an exaggerated host immune response to a dysbiotic microbial community.
  • To know that advances in immunotherapeutic interventions to neutralize microbial virulence factors and pro-inflammatory mediators may have utility in the prevention and treatment of human diseases including periodontal diseases.
Presentation Date
June 23, 2022

Presenters
Richard Lamont - The Oral Microbiome in Homeostasis and Dysbiosis
Jan Potempa -  The Molecular Basis of Microbial Virulence in Periodontitis and Systemic Disease
Eric Reynolds - Neutralising Polymicrobial Virulence Factors to Revert Dysbiosis to Homeostasis
George Hajishengallis -  From Immune Pathways and Preclinical Models to Therapies in Human Oral Disease

Sponsoring Groups/Networks
Cariology Research, Pediatric Oral Health Research

CE Credits
1.5 Hours

Financial Interest Disclosure:
None


Not eligible for individual purchase must purchase as part of a meeting bundle.