2022 IADR/APR General Session
The 100 th General Session & Exhibition of the IADR was held in conjunction with the 5th Meeting of the Asia Pacific Region. The virtual meeting was attended by individuals from around the world. Those attending the meeting could choose from among 207 Interactive Talk sessions, seven Focused Learning Sessions, three Hands-on Workshops, five satellite symposia, 52 Symposia, one Distinguished Lecture Series and a plenary.The recordings in this library from the meeting are a selection of the science that was to be presented as part of the General Session. These recordings give you the opportunity to participate in the meeting and hear from leading researchers. The recordings include the IADR Distinguished Lecture Series speaker and symposia from a collection of scientific groups and networks.
This session can be purchased as part of the full meeting recordings within the product bundles
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Session Description
The term “bioactivity” is used frequently in oral health research, but with little agreement about an actual definition, or about what specifically makes something “bioactive.” Bioactive has been defined as having a biological effect, having an effect on a living organism, or having an effect on a living organism, tissue, or cell. The bioactivity of certain endogenous molecules is obvious when they promote specific cellular or tissue responses under appropriate conditions. But must foreign molecules or materials that enter the body or oral cavity elicit a biological response to be considered “bioactive?” And how do we define “biological response?”
Throughout the literature are descriptions of “bioactive” materials that are involved in a variety of activities, including promoting mineralization of bone or teeth, inducing the recruitment and/or differentiation of resident cells to perform specific functions, or exerting an antimicrobial, antifouling, pH buffering, or biofilm modulating effect. However, mineralization and pH buffering may simply be chemical effects where ions released under appropriate conditions nucleate and grow new mineralized tissues on or near the material. Is this bioactivity? A material that releases ions under acidic conditions may neutralize the environment, but is this really a bioactive material? This growing field shows great promise for improving oral health care, but also creates much confusion and potential for misinformation through marketing. The goal of this symposium is to provide some clarity to the concept of bioactivity as it relates to dental materials, using examples from restorative and implant dentistry, and tissue engineering/regeneration.
Learning Objectives
June 24, 2022
Presenters
Mary Anne Melo - What Does Bioactivity Imply With Dental Restorative Materials?
In-Sung Yeo - Do Surface Treatments Make Dental Implants Bioactive?
Anibal Diogenes - Does Successful Tissue Engineering and Regeneration Rely on Bioactivity?
Brian Darvell - Reaction to the Presentations – Sorting it all out
Sponsoring Groups/Networks
Dental Materials, Implantology Research, Mineralized Tissue, Pulp Biology & Regeneration Research
CE Credits
1.5 Hours
Financial Interest Disclosure:
None
The term “bioactivity” is used frequently in oral health research, but with little agreement about an actual definition, or about what specifically makes something “bioactive.” Bioactive has been defined as having a biological effect, having an effect on a living organism, or having an effect on a living organism, tissue, or cell. The bioactivity of certain endogenous molecules is obvious when they promote specific cellular or tissue responses under appropriate conditions. But must foreign molecules or materials that enter the body or oral cavity elicit a biological response to be considered “bioactive?” And how do we define “biological response?”
Throughout the literature are descriptions of “bioactive” materials that are involved in a variety of activities, including promoting mineralization of bone or teeth, inducing the recruitment and/or differentiation of resident cells to perform specific functions, or exerting an antimicrobial, antifouling, pH buffering, or biofilm modulating effect. However, mineralization and pH buffering may simply be chemical effects where ions released under appropriate conditions nucleate and grow new mineralized tissues on or near the material. Is this bioactivity? A material that releases ions under acidic conditions may neutralize the environment, but is this really a bioactive material? This growing field shows great promise for improving oral health care, but also creates much confusion and potential for misinformation through marketing. The goal of this symposium is to provide some clarity to the concept of bioactivity as it relates to dental materials, using examples from restorative and implant dentistry, and tissue engineering/regeneration.
Learning Objectives
- Describe the various effects that are attributed to bioactivity as they relate to the development of new dental materials
- Explain the difference between a broad and a focused definition of bioactive materials, giving specific examples
- Identify indications for bioactive materials in restorative, implant, and regenerative dentistry
June 24, 2022
Presenters
Mary Anne Melo - What Does Bioactivity Imply With Dental Restorative Materials?
In-Sung Yeo - Do Surface Treatments Make Dental Implants Bioactive?
Anibal Diogenes - Does Successful Tissue Engineering and Regeneration Rely on Bioactivity?
Brian Darvell - Reaction to the Presentations – Sorting it all out
Sponsoring Groups/Networks
Dental Materials, Implantology Research, Mineralized Tissue, Pulp Biology & Regeneration Research
CE Credits
1.5 Hours
None
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