2022 IADR/APR General Session
The 100 th General Session & Exhibition of the IADR was held in conjunction with the 5th Meeting of the Asia Pacific Region. The virtual meeting was attended by individuals from around the world. Those attending the meeting could choose from among 207 Interactive Talk sessions, seven Focused Learning Sessions, three Hands-on Workshops, five satellite symposia, 52 Symposia, one Distinguished Lecture Series and a plenary.The recordings in this library from the meeting are a selection of the science that was to be presented as part of the General Session. These recordings give you the opportunity to participate in the meeting and hear from leading researchers. The recordings include the IADR Distinguished Lecture Series speaker and symposia from a collection of scientific groups and networks.
This session can be purchased as part of the full meeting recordings within the product bundles
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Session Description
It is generally accepted that Asians including Japanese are more susceptible to obesity-related disorder such as diabetes. In this context, although screening for type 2 diabetes is recommended for the subjects whose BMI over 25 kg/m2 in general population, BMI over 23 kg/m2 is suggested for Asians. Periodontal disease is typical complication of obesity as well as diabetes. Therefore, it is essential to understand the nature of periodontal disease according to the distinct ethnic group with diverse degree of obesity. In this proposal, we first summarize the association between metabolic control of type 2 diabetes and PISA /PESA in Japanese subjects and withdraw the clinical feature of diabetes whose HbA1c was potentially influenced by periodontal inflammation. We next focus on insulin resistance caused by the obesity-related inflammation and unveil the molecular basis as to how insulin resistance affects periodontal pathogenesis. Obesity is characterized by adipocyte maturation. Therefore, it is essential to establish novel therapeutic strategy preventing the maturation of adipocytes. In this context, recently, photoreceptor Opsin 3 was found to be expressed on adipocytes. We discuss about the possible use of Opn3-based phototherapy against obesity (PLoS Biol, 2020). Besides such innovative technology, both diet and exercise are fundamental therapeutic approach against obesity. Here we re-consider the importance of exercise to establish future molecular targeted therapy by identifying molecules influenced by exercise (Cell Metab, 2021).
Many parts of the studies in these presentations were carried out at Joslin Diabetes Center under the support of Sunstar Foundation, Osaka, Japan.
Learning Objectives
June 23, 2022
Presenters
Koji Mizutani - Updating of a Bilateral Link of Periodontitis and Diabetes Based on the Latest Investigations in Japan
Takanori Shinjo - Insulin Resistance and Obesity-Related Periodontitis: a Novel Molecular Basis and Potential Therapeutic Targets
Tadataka Tsuji - Light Therapy for fat Metabolism via Photoreceptor Opsin3
Joji Kusuyama - Molecular Mechanisms of Exercise That can Transform and Improve our Future Health
Sponsoring Groups/Networks
Periodontal Research
CE Credits
1.5 Hours
Financial Interest Disclosure:
None
It is generally accepted that Asians including Japanese are more susceptible to obesity-related disorder such as diabetes. In this context, although screening for type 2 diabetes is recommended for the subjects whose BMI over 25 kg/m2 in general population, BMI over 23 kg/m2 is suggested for Asians. Periodontal disease is typical complication of obesity as well as diabetes. Therefore, it is essential to understand the nature of periodontal disease according to the distinct ethnic group with diverse degree of obesity. In this proposal, we first summarize the association between metabolic control of type 2 diabetes and PISA /PESA in Japanese subjects and withdraw the clinical feature of diabetes whose HbA1c was potentially influenced by periodontal inflammation. We next focus on insulin resistance caused by the obesity-related inflammation and unveil the molecular basis as to how insulin resistance affects periodontal pathogenesis. Obesity is characterized by adipocyte maturation. Therefore, it is essential to establish novel therapeutic strategy preventing the maturation of adipocytes. In this context, recently, photoreceptor Opsin 3 was found to be expressed on adipocytes. We discuss about the possible use of Opn3-based phototherapy against obesity (PLoS Biol, 2020). Besides such innovative technology, both diet and exercise are fundamental therapeutic approach against obesity. Here we re-consider the importance of exercise to establish future molecular targeted therapy by identifying molecules influenced by exercise (Cell Metab, 2021).
Many parts of the studies in these presentations were carried out at Joslin Diabetes Center under the support of Sunstar Foundation, Osaka, Japan.
Learning Objectives
- To learn the diverse susceptibility to periodontal disease in Asian population with diabetes and its influences on metabolic control of diabetes
- To learn the most recent research on the prevention of adipocyte maturation and the effect of excersise at molecular level to overcome unwanted side effects of obesity such as insulin resistance and periodontal disease
June 23, 2022
Presenters
Koji Mizutani - Updating of a Bilateral Link of Periodontitis and Diabetes Based on the Latest Investigations in Japan
Takanori Shinjo - Insulin Resistance and Obesity-Related Periodontitis: a Novel Molecular Basis and Potential Therapeutic Targets
Tadataka Tsuji - Light Therapy for fat Metabolism via Photoreceptor Opsin3
Joji Kusuyama - Molecular Mechanisms of Exercise That can Transform and Improve our Future Health
Sponsoring Groups/Networks
Periodontal Research
CE Credits
1.5 Hours
None
Not eligible for individual purchase; must purchased as part of a meeting bundle.
