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Oral Microbiome Data Analysis: New Challenges, Analysis Methods and Applications

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2022 IADR/APR General Session

The 100 th General Session & Exhibition of the IADR was held in conjunction with the 5th Meeting of the Asia Pacific Region. The virtual meeting was attended by individuals from around the world. Those attending the meeting could choose from among 207 Interactive Talk sessions, seven Focused Learning Sessions, three Hands-on Workshops, five satellite symposia, 52 Symposia, one Distinguished Lecture Series and a plenary. 

The recordings in this library from the meeting are a selection of the science that was to be presented as part of the General Session. These recordings give you the opportunity to participate in the meeting and hear from leading researchers. The recordings include the IADR Distinguished Lecture Series speaker and symposia from a collection of scientific groups and networks.

This session can be purchased as part of the full meeting recordings within the product bundles

Bacterial dysbiosis has been implicated in various clinical dental conditions, e.g., caries, periodontitis and oral cancer. Microbial diversity, community composition and abundance can be captured by microbiome DNA sequencing for the questions “what bacteria are there?”, while metatranscriptomics through mRNA sequencing identifies functional characterization of complex microbial communities to answer “what the bacteria do there”. Although challenges of handling these two levels of data remain, the oral microbiome sequencing data analysis has its unique features in terms of reference genome and bacteria diversity. In additon, metabolomics is key for understanding the relation between the microbial and general biological activities associated with diseases. Given the growing interest in better handling the data and understanding the connection between data analysis and the research/clinical questions, this symposium outlines the recent advances in oral microbiome data analysis, with the interesting and important applications to understand oral health problems and how to leverage the Oral Host-Microbial Markers in COVID-19. This goal wil be deliverd by covering comprehensive topics and showcasing the most recent results in these fields. We propose to introduce the cutting edge computational methods and data analysis pipelines for microbiome data (differential abundance test and omics data integration). The health domains to address include infant oral microbiome, COVID-19, periodontal disease and Earlier Childhood Careis (ECC). As age is a facor affecting microbiome, the cohorts in our talks include infants, preschool children and adults. The microbiome landscape and their interactions with metabolome at the different body sites (gut and oral) will also be discussed.

Learning Objectives
  • Undersatnd the basic landscape of infant oral microbiome
  • Learn the role of oral host-microbial markers in COVID-19
  • Learn the idea of differential abundance analysis and data integration for oral microbiome data

Presentation Date

June 24, 2022

Stuart Dashper - The Infant Oral Microbiome in Health and Disease
Marcelo Freire - Harnessing Oral Host-Microbial Markers in COVID-19
Gen Li - Novel Association and Differential Abundance Analysis of the Oral Microbiome and Periodontal Disease
Di Wu - Microbial Omics Data Integration to Compare Oral and gut Bacterial Association With Diseases (ECC and IBD)

Sponsoring Groups/Networks
Microbiology/Immunology, Pediatric Oral Health Research

CE Credits
Not Eligible

Financial Interest Disclosure:

Not eligible for individual purchase must purchase as part of a meeting bundle.