2022 IADR/APR General Session
The 100 th General Session & Exhibition of the IADR was held in conjunction with the 5th Meeting of the Asia Pacific Region. The virtual meeting was attended by individuals from around the world. Those attending the meeting could choose from among 207 Interactive Talk sessions, seven Focused Learning Sessions, three Hands-on Workshops, five satellite symposia, 52 Symposia, one Distinguished Lecture Series and a plenary.The recordings in this library from the meeting are a selection of the science that was to be presented as part of the General Session. These recordings give you the opportunity to participate in the meeting and hear from leading researchers. The recordings include the IADR Distinguished Lecture Series speaker and symposia from a collection of scientific groups and networks.
This session can be purchased as part of the full meeting recordings within the product bundles
Description
The insertion of a dental implant triggers the local immune response for its ‘foreign body’ nature. Evolution of the related immune concept progressively shifts from an inflammatory response that is ultimately responsible for fibrotic encapsulation to what incorporates, regulates and even encourages osseointegration. The immune system response and inflammation require well-engaged and active biochemical processes to restore homeostasis, which consequently leads to osseointegration of implant. Studies have suggested distinct immune profile in surrounding bone and peri-implant soft tissue under physiological and pathological conditions, with specific compositional characteristics, differentiation status and functional cytokines detected by immunohistological and immunohistochemical analysis. Peri-implantitis is a major cause of implant failure and is considered a microbiome and immune-driven disease. Aggregation of innate and adaptive immune cells and elevated levels of pro-inflammatory cytokines was observed in peri-implantitis sites. Based on these findings, utilizing immunomodulatory surgeries and implantation of immunomodulatory biomaterials that polarize the pro-inflammatory microenvironment towards the pro-regenerative microenvironment would be potential strategies targeting at resolution of peri-implant disease and regeneration of peri-implant tissue. Nevertheless, the heterogeneity of immune response and the mechanisms engaged remains largely unexplored. This symposium will explore the possible mechanisms of immune regulation in implant dentistry. Immunomodulatory surgeries and biomaterials will also be discussed.
Learning Objectives
Presentation Date
June 23, 2022
Presenters
Yi Man - Exploring the Immune Homeostasis in Periodontal Soft Tissue and Strategies to Restore a pro-Regenerative Microenvironment
Zetao Chen - Immunomodulation Based Strategy for the Development of Dental Regenerative Materials
Katarzyna Gurzawska - Immune-Instructive Biomaterials to Promote Bone Regeneration
Yuelian Liu - Osteoinduction and Osteointergration in Implant Dentistry
Sponsoring Groups/Networks
Dental Materials, Implantology Research, Prosthodontics Research
CE Credits
Not Eligible
Financial Interest Disclosure:
None
The insertion of a dental implant triggers the local immune response for its ‘foreign body’ nature. Evolution of the related immune concept progressively shifts from an inflammatory response that is ultimately responsible for fibrotic encapsulation to what incorporates, regulates and even encourages osseointegration. The immune system response and inflammation require well-engaged and active biochemical processes to restore homeostasis, which consequently leads to osseointegration of implant. Studies have suggested distinct immune profile in surrounding bone and peri-implant soft tissue under physiological and pathological conditions, with specific compositional characteristics, differentiation status and functional cytokines detected by immunohistological and immunohistochemical analysis. Peri-implantitis is a major cause of implant failure and is considered a microbiome and immune-driven disease. Aggregation of innate and adaptive immune cells and elevated levels of pro-inflammatory cytokines was observed in peri-implantitis sites. Based on these findings, utilizing immunomodulatory surgeries and implantation of immunomodulatory biomaterials that polarize the pro-inflammatory microenvironment towards the pro-regenerative microenvironment would be potential strategies targeting at resolution of peri-implant disease and regeneration of peri-implant tissue. Nevertheless, the heterogeneity of immune response and the mechanisms engaged remains largely unexplored. This symposium will explore the possible mechanisms of immune regulation in implant dentistry. Immunomodulatory surgeries and biomaterials will also be discussed.
Learning Objectives
- To recognize the bone and soft tissue immune response to dental implants.
- To present the immune profile and possible mechanisms of immune regulation under physiological and pathological conditions.
- To present immunomodulatory surgeries and design of immunomodulatory biomaterials.
Presentation Date
June 23, 2022
Presenters
Yi Man - Exploring the Immune Homeostasis in Periodontal Soft Tissue and Strategies to Restore a pro-Regenerative Microenvironment
Zetao Chen - Immunomodulation Based Strategy for the Development of Dental Regenerative Materials
Katarzyna Gurzawska - Immune-Instructive Biomaterials to Promote Bone Regeneration
Yuelian Liu - Osteoinduction and Osteointergration in Implant Dentistry
Sponsoring Groups/Networks
Dental Materials, Implantology Research, Prosthodontics Research
CE Credits
Not Eligible
None
Not eligible for individual purchase must purchase as part of a meeting bundle.