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Engineering of Oral Microbiota in the Omics Era

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2023 AADOCR/CADR Annual Meeting

The 2023 AADOCR/CADR Annual Meeting & Exhibition provided dental, oral, and craniofacial health scientists with the opportunity to present, discuss, and critique their latest and most cutting-edge research at a 100% in-person gathering in Portland, Oregon. The meeting was attended by 2,054 individuals from 39 countries.     

The recordings in this library from the meeting are a selection of the science that was presented at the Annual Meeting. These recordings give you the opportunity to participate in the meeting and hear from leading researchers. The recordings include IADR Distinguished Lecture Series speakers and symposia from a collection of scientific groups and networks.

This session can be purchased as part of the full meeting recordings within the product bundles





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Session Description 
Microbiome, genomics, proteomics and metabolomics studies have expanded our understanding of vast diversities in microbial compositions and their potential activities within the oral cavity. Despite these advances, little is known about microbial virulence and pathogenesis, which is largely due to the lack of reliable genetic systems that can efficiently and effectively manipulate organisms of interests that may be closely linked to the local and systemic diseases. In this symposium we invited 4 speakers who are expert in the development of new genetic engineering tools in their efforts to study oral microbiota. They have agreed to present their research in the areas of characterizing different oral microbes including Fusobacterium nucleatum, Parvimonas micra, Treponema denticola and Streptococcus mutans and studying their role as a ubiquitous pathobiont in oral and systemic conditions. The symposium will bring different expertise from both dental schools and medical schools together to highlight new findings using the state of art technologies. Members from various scientific research groups including Microbiology/Immunology research group, Periodontal Research Group and Cariology Research Group would be interested in this topic.

Learning Objectives
  • Providing updated research advances in the area of genetically manipulating oral microbiota especially microbes whose genetic systems are not tractable
  • Learning CRISPR-based and other state of art technologies that have been successfully used in the precision engineering of anaerobic organisms
  • Learning how new emerging pathobiont being studied based on their omics information
Presentation Date
Thursday, March 16, 2023

Presenters
  • Robert Shields - CRISPR-based functional genomics of unknown genes in oral microbiota
  • J. Christopher Christopher Fenno - Genetic engineering of Treponema denticola by evasion of the restriction and modification barrier
  • Chenggang Wu - Forward genetic approach for Fusobacterium nucleatum
  • Justin Merritt - Genetic manipulation of Parvimonas micra, a ubiquitous pathobiont
Sponsoring Groups/Networks
Microbiology/Immunology

CE Credits
Not Eligible

Financial Interest Disclosure:
None

Not eligible for individual purchase must purchase as part of a meeting bundle.