2023 AADOCR/CADR Annual Meeting
The 2023 AADOCR/CADR Annual Meeting & Exhibition provided dental, oral, and craniofacial health scientists with the opportunity to present, discuss, and critique their latest and most cutting-edge research at a 100% in-person gathering in Portland, Oregon. The meeting was attended by 2,054 individuals from 39 countries.The recordings in this library from the meeting are a selection of the science that was presented at the Annual Meeting. These recordings give you the opportunity to participate in the meeting and hear from leading researchers. The recordings include IADR Distinguished Lecture Series speakers and symposia from a collection of scientific groups and networks.
This session can be purchased as part of the full meeting recordings within the product bundles
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Session Description
Following radiotherapy for the treatment of head and neck cancers, most patients experience loss of salivary function, often permanently. Hyposalivation as a result of radiotherapy or other salivary gland diseases (e.g., autoimmune Sjogren's), often leads to a host of health complications that reduce patient quality of life, including increased incidence of dental caries and oral infections, loss of taste, and difficulties swallowing or speaking. Current therapeutics, including artificial saliva and muscarinic receptor agonists to induce secretion, only provide temporary symptom relief. Thus, significant focus has been on understanding the regenerative process and using those findings to develop novel therapeutic strategies. This work, aided by innovative new techniques, has unveiled a diverse set of cellular players in the regenerative process. In this session, investigators who each study different cellular compartments in salivary gland regeneration, present their recent findings. This session aims to generate a more holistic picture of salivary gland regeneration and the cellular functions and signaling involved in the regenerative process.
Learning Objectives
Thursday, March 16, 2023
Presenters
Salivary Research
CE Credits
1.5 Hours
Financial Interest Disclosure:
NONE
Following radiotherapy for the treatment of head and neck cancers, most patients experience loss of salivary function, often permanently. Hyposalivation as a result of radiotherapy or other salivary gland diseases (e.g., autoimmune Sjogren's), often leads to a host of health complications that reduce patient quality of life, including increased incidence of dental caries and oral infections, loss of taste, and difficulties swallowing or speaking. Current therapeutics, including artificial saliva and muscarinic receptor agonists to induce secretion, only provide temporary symptom relief. Thus, significant focus has been on understanding the regenerative process and using those findings to develop novel therapeutic strategies. This work, aided by innovative new techniques, has unveiled a diverse set of cellular players in the regenerative process. In this session, investigators who each study different cellular compartments in salivary gland regeneration, present their recent findings. This session aims to generate a more holistic picture of salivary gland regeneration and the cellular functions and signaling involved in the regenerative process.
Learning Objectives
- Learn about recent studies, including those using innovative omics technologies, and how they illuminate the cellular diversity of salivary gland regeneration.
- Generate a more holistic view of the diverse cellular players and their interactions in the salivary gland regenerative process.
- Learn how current knowledge on the mechanisms of salivary gland regeneration and the cellular players can inform therapeutic strategies for regaining salivary function.
Thursday, March 16, 2023
Presenters
- Rose-Anne Romano - Cellular plasticity and diversity that underlie salivary gland homeostasis and regeneration
- Melinda Larsen - Single Cell RNA Sequencing-Based Approaches for Understanding Salivary Gland Regeneration
- Fei Liu - Roles of resident macrophages in the development, homeostasis, and regeneration of salivary glands
- Siva V - Desert hedgehog signaling coordinates salivary gland regeneration via mesenchyme
Salivary Research
CE Credits
1.5 Hours
NONE
