2023 IADR/LAR General Session with WCPD
The 2023 IADR/LAR General Session & Exhibition with WCPD provided dental, oral, and craniofacial health scientists with the opportunity to present, discuss, and critique their latest and most cutting-edge research at a 100% in-person gathering in Bogotá, Colombia. The meeting was attended by 1,667 individuals from 76 countries.The recordings in this library from the meeting are a selection of the science that was presented at the General Session. These recordings give you the opportunity to participate in the meeting and hear from leading researchers. The recordings include IADR Distinguished Lecture Series speakers and symposia from a collection of scientific groups and networks.
This session can be purchased as part of the full meeting recordings within the product bundles
The International Association for Dental Research is an ADA CERP Recognized Provider. ADA CERP is a service of the American Dental Association to assist dental professionals in identifying quality providers of continuing dental education. ADA CERP does not approve or endorse individual courses or instructors, nor does it imply acceptance of credit hours by boards of dentistry. Concerns or complaints about a CE provider may be directed to the provider or to the Commission for Continuing Education Provider Recognition at ADA.org/CERP.
Session Description
Contemporary dentistry is moving away from the mostly reparative dentistry of the 20th century and toward a minimally invasive (MI) strategy that includes up-to-date detection and risk assessment before making a treatment decision. Detection, prevention, and control of oral disease using minimally invasive (MI) procedures are the fundamental principles for preserving hard and soft tissues in oral cavity. In this respect, saliva plays a crucial role in MI strategies for the management of dental diseases. Its potential merits rest on the fact that it can be easily, repeatedly, and non-invasively obtained. Therefore, this biofluid is widely considered as a novel diagnostic method for both systematic and oral diseases.
Saliva is a versatile body fluid and represents a non-invasive and safe study specimen, being especially useful in large-scale studies. The devasting COVID-19 pandemic has claimed the lives of over 5 million people globally. COVID-19 is caused by a novel Beta coronavirus, Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) and the virus establishes infection mainly through mucosal cells found in the nose and lungs. Since the oral cavity is an important site of infection, specifically the role of the oral microbiome in COVID-19 infection is likely to play an important role in viral infection. Interesting early findings showed that the oral bacteria isolated from human saliva samples were capable of either promoting or inhibiting SARS-CoV-2 infection in vitro. Certain bacterial species (i.e., Porphyromonas gingivalis) were found to inhibit infection. The identification of factors produced by oral bacteria that can modulate COVID-19 infection has just begun. The mechanisms by which oral bacterial factors in the saliva can mediate either enhancement or inhibition of infection will be discussed. These studies underscore the importance of the saliva, oral microbiome in SARS-CoV-2 infection and transmission.
Periodontitis is one of the main causes for tooth loss and affecting billions of people worldwide. This infectious disease has an inflammatory character, where chronic and uncontrolled immune inflammatory responses initiate the process that leads to destruction of tooth-supporting tissues and, if untreated, eventually to tooth loss. Supportive tissue damage around the tooth can be measured by using clinical or radiographical indices. The salivary presence of periodontal pathogens, which initiate the inflammatory conditions in periodontal tissues, is associated with periodontitis. During the onset and progress of periodontitis, inflammatory markers are released from cells of the periodontium. Elevated levels of enzymes, cytokines, and biomarkers of connective tissue destruction and bone turnover can be found in saliva of periodontitis patients in comparison to their controls. Furthermore, there is considerable interest in applying sequencing and genotyping studies in various human populations. Whole blood is then the traditional sample of choice; however, obtaining a blood sample is an invasive procedure that requires training in phlebotomy. However, saliva offers an efficient source for genetic information. It has been demonstrated that, compared with cheek swabs, saliva samples provide a substantial increase in the amount of human DNA. The present presentation will aim to demonstrate the current evidence on salivary markers as being potential tool to detect periodontal treatment need and to predict periodontal treatment outcome.
In conclusion, early detection of dental diseases always minimises the need for invasive management strategies. In this respect, saliva is an undiscovered ocean and could be a powerful detection tool if utilised effectively.
Learning Objectives
Friday, June 23, 2023
Session Organizer/Chair
Aylin Baysan (Organizer/Chair)
Presenters
Minimally Invasive Dentistry Network
CE Credits
Not Eligible
Financial Interest Disclosure:
NONE
Contemporary dentistry is moving away from the mostly reparative dentistry of the 20th century and toward a minimally invasive (MI) strategy that includes up-to-date detection and risk assessment before making a treatment decision. Detection, prevention, and control of oral disease using minimally invasive (MI) procedures are the fundamental principles for preserving hard and soft tissues in oral cavity. In this respect, saliva plays a crucial role in MI strategies for the management of dental diseases. Its potential merits rest on the fact that it can be easily, repeatedly, and non-invasively obtained. Therefore, this biofluid is widely considered as a novel diagnostic method for both systematic and oral diseases.
Saliva is a versatile body fluid and represents a non-invasive and safe study specimen, being especially useful in large-scale studies. The devasting COVID-19 pandemic has claimed the lives of over 5 million people globally. COVID-19 is caused by a novel Beta coronavirus, Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) and the virus establishes infection mainly through mucosal cells found in the nose and lungs. Since the oral cavity is an important site of infection, specifically the role of the oral microbiome in COVID-19 infection is likely to play an important role in viral infection. Interesting early findings showed that the oral bacteria isolated from human saliva samples were capable of either promoting or inhibiting SARS-CoV-2 infection in vitro. Certain bacterial species (i.e., Porphyromonas gingivalis) were found to inhibit infection. The identification of factors produced by oral bacteria that can modulate COVID-19 infection has just begun. The mechanisms by which oral bacterial factors in the saliva can mediate either enhancement or inhibition of infection will be discussed. These studies underscore the importance of the saliva, oral microbiome in SARS-CoV-2 infection and transmission.
Periodontitis is one of the main causes for tooth loss and affecting billions of people worldwide. This infectious disease has an inflammatory character, where chronic and uncontrolled immune inflammatory responses initiate the process that leads to destruction of tooth-supporting tissues and, if untreated, eventually to tooth loss. Supportive tissue damage around the tooth can be measured by using clinical or radiographical indices. The salivary presence of periodontal pathogens, which initiate the inflammatory conditions in periodontal tissues, is associated with periodontitis. During the onset and progress of periodontitis, inflammatory markers are released from cells of the periodontium. Elevated levels of enzymes, cytokines, and biomarkers of connective tissue destruction and bone turnover can be found in saliva of periodontitis patients in comparison to their controls. Furthermore, there is considerable interest in applying sequencing and genotyping studies in various human populations. Whole blood is then the traditional sample of choice; however, obtaining a blood sample is an invasive procedure that requires training in phlebotomy. However, saliva offers an efficient source for genetic information. It has been demonstrated that, compared with cheek swabs, saliva samples provide a substantial increase in the amount of human DNA. The present presentation will aim to demonstrate the current evidence on salivary markers as being potential tool to detect periodontal treatment need and to predict periodontal treatment outcome.
In conclusion, early detection of dental diseases always minimises the need for invasive management strategies. In this respect, saliva is an undiscovered ocean and could be a powerful detection tool if utilised effectively.
Learning Objectives
- To be able to understand the principles of minimally invasive strategies and importance of early detection for the management of dental diseases.
- To appreciate the biofluid: Saliva as noninvasive and innovational detection tool
- To explore the importance of the saliva, oral microbiome in SARS-CoV-2 infection and transmission.
To understand the role of salivary markers as being potential tool to detect periodontal treatment need and to predict periodontal treatment outcome.
Friday, June 23, 2023
Session Organizer/Chair
Aylin Baysan (Organizer/Chair)
Presenters
- Aylin Baysan - Maximum Impact using Early Detection: Decoding Saliva
- Mark Cayabyab - The mouth- A window to Covid-19 infection
- Ulvi Gursoy - Are Salivary Diagnostics next generation innovation?
Minimally Invasive Dentistry Network
CE Credits
Not Eligible
NONE
Not eligible for individual purchase must purchase as part of a meeting bundle.