2023 IADR/LAR General Session with WCPD
The 2023 IADR/LAR General Session & Exhibition with WCPD provided dental, oral, and craniofacial health scientists with the opportunity to present, discuss, and critique their latest and most cutting-edge research at a 100% in-person gathering in Bogotá, Colombia. The meeting was attended by 1,667 individuals from 76 countries.The recordings in this library from the meeting are a selection of the science that was presented at the General Session. These recordings give you the opportunity to participate in the meeting and hear from leading researchers. The recordings include IADR Distinguished Lecture Series speakers and symposia from a collection of scientific groups and networks.
This session can be purchased as part of the full meeting recordings within the product bundles
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Session Description
There is an ongoing war that killed an estimated 4.95 million people in the past year, and it is likely that this war will kill 10 million people by 2050 and yet, we do not have the adequate weaponry to tackle our common enemy – pathogenic bacteria and yeasts. It is now apparent that antibiotics and antifungals fall short of what we need in terms of eradicating potent pathogens. Meanwhile, current antimicrobials lack the ability to modulate host immune-inflammatory response or enhance tissue healing. However, one category of compounds composed of sequences of amino acids i.e.., peptides and their mimics have the potential to be tuned to offer a range of biological functions ranging from antimicrobial, antibiofilm, antifouling applications to anti-inflammatory, immune-modulatory and tissue engineering functions. While such peptides have been extensively studied in both their tethered and non-tethered forms, clinical translation has been severely limited to their potential toxicity and degradation in biological matrices and microbial enzymes. Peptoids are a potential solution to this problem and have shown antibacterial and antiviral functions. In this symposium, we are delighted to present expert talks by scientists who have demonstrated fantastic research based on peptides and peptoids for a broad range of biological applications.
Learning Objectives
Saturday, June 24, 2023
Session Organizer/Chair
Lisa Ryan (Organizer)
César de la Fuente (Organizer)
Prasanna Neelakantan (Organizer/Chair)
Gill Diamond (Organizer)
Presenters
Microbiology/Immunology
CE Credits
1.5 Hours
Financial Interest Disclosure:
NONE
There is an ongoing war that killed an estimated 4.95 million people in the past year, and it is likely that this war will kill 10 million people by 2050 and yet, we do not have the adequate weaponry to tackle our common enemy – pathogenic bacteria and yeasts. It is now apparent that antibiotics and antifungals fall short of what we need in terms of eradicating potent pathogens. Meanwhile, current antimicrobials lack the ability to modulate host immune-inflammatory response or enhance tissue healing. However, one category of compounds composed of sequences of amino acids i.e.., peptides and their mimics have the potential to be tuned to offer a range of biological functions ranging from antimicrobial, antibiofilm, antifouling applications to anti-inflammatory, immune-modulatory and tissue engineering functions. While such peptides have been extensively studied in both their tethered and non-tethered forms, clinical translation has been severely limited to their potential toxicity and degradation in biological matrices and microbial enzymes. Peptoids are a potential solution to this problem and have shown antibacterial and antiviral functions. In this symposium, we are delighted to present expert talks by scientists who have demonstrated fantastic research based on peptides and peptoids for a broad range of biological applications.
Learning Objectives
- Understand the role of peptides in innate immune responses against microbial infections
- Describe the effects of peptides and peptoids against bacterial and fungal pathogens and comunity shaping at large
- Apply novel and innovative concepts of discovering peptide antibiotics
Saturday, June 24, 2023
Session Organizer/Chair
Lisa Ryan (Organizer)
César de la Fuente (Organizer)
Prasanna Neelakantan (Organizer/Chair)
Gill Diamond (Organizer)
Presenters
- Lisa Ryan - Beyond the Antiviral Effects of Defensins: SARS-CoV2 and Its Grip on Host Defense in the Oral Cavity and the Gut
- Prasanna Neelakantan - Antifungal Peptides and Improved Delivery Platforms
- Gill Diamond - Activity of Antimicrobial Peptoids Against Oral Pathogens
- Octavio Franco - Artificial Intelligence Approaches for Peptide Antibiotic Discovery.
Microbiology/Immunology
CE Credits
1.5 Hours
NONE
