This lecture will introduce the audience to the rapidly expanding field of optogenetics, a powerful tool for manipulating the activity of individual neurons in the brain. The lecture will describe the development of new technologies enabling the implementation of optogenetics in freely moving mice, and demonstrate how these tools can be deployed to better understand neural circuitry underlying pain. The lecture will also describe a proof of concept study in animal models demonstrating the potential utility of optogenetics for the nonpharmacologic treatment of ongoing pain.
Learning Objectives:
Upon completion, participants will be able to:
- Understand the concept of optogenetics, and describe key technological components necessary to use this technique.
- Describe different strategies for delivering light to the nervous system to imlement optogenetics in vivo.
- Understand the potential of optogenetic approaches for the treatment of pain.
Credit: This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of Annenberg Center for Health Sciences at Eisenhower and the International Association for the Study of Pain. The Annenberg Center for Health Sciences at Eisenhower is accredited by the ACCME to provide continuing medical education for physicians.
The Annenberg Center for Health Sciences at Eisenhower designates this enduring activity for a maximum of 0.5 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
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