Skip to main content

Establishing the Diagnosis of Small Fiber Neuropathy – Corneal Confocal Microscopy is Superior to Skin Punch Biopsy

This debate will discuss advantages and disadvantages of corneal confocal microscopy (CCM) in contrast to assessing the intraepidermal nerve fiber density via skin biopsy in assessing the structure of small fibers in patients with neuropathy or with neuropathic pain states. Proponents of CCM and IENFD will advocate their points of view; afterwards, each will reply to the other’s critique.

Learning Objectives:
Upon completion, participants will be able to:

  • Define the challenges linked to the diagnosis of small fiber neuropathy.
  • Be shown how corneal confocal microscopy can be used as a non-invasive method for assessing small fiber density in the cornea, as a biomarker for small fiber neuropathy.
  • Be presented the gold standard of small fiber rarefication, intraepidermal punch biopsy, and its applications for research and diagnosis.

Credit: This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of Annenberg Center for Health Sciences at Eisenhower and the International Association for the Study of Pain. The Annenberg Center for Health Sciences at Eisenhower is accredited by the ACCME to provide continuing medical education for physicians.

The Annenberg Center for Health Sciences at Eisenhower designates this enduring activity for a maximum of 0.5 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Please log in at the top right corner of the page with your IASP credentials. To access the free recording, please select the presentation icon below. Survey and CME credit are available for a small fee after viewing the presentation.

Nonmembers must first join IASP for access.