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This past February, the Rita Allen Foundation named their 2021 class of Award in Pain Scholars, celebrating four early-career leaders in the biomedical sciences whose research holds exceptional promise for revealing new pathways to understand and treat chronic pain. IASP and PRF are excited to host two webinars, featuring two 2021 Award in Pain Scholars each, to learn more about their work to expand the understanding of chronic pain and its widespread societal impact.
In Part 1, presentations will be given by:
-- Aaron Mickle, PhD, University of Florida, USA
Urothelial Cells and Bladder Sensory Signaling
-- Nicole Scheff, PhD, University of Pittsburgh, USA.
The Impact of CGRP Neurotransmission on Head and Neck Cancer Pain and Progression
In oral squamous cell carcinoma, pain is a primary feature and calcitonin gene-related peptide (CGRP)-releasing sensory nerves dominate tumor innervation. CGRP signaling drives a pro-tumor microenvironment by limiting immunosurveillance of cancer suggesting that blockade of CGRP release from tumor-innervating sensory nerves may be a viable therapeutic strategy to reduce pain and slow cancer progression.
This session will be moderated by:
-- Edgar Alfonso Romero-Sandoval, MD, PhD, Wake Forest University School of Medicine, North Carolina, USA