Description
Webinar 2 of 2:
What’s an Estimand and Why Should I Use It?
Organized By: Statistics SIG
What’s an Estimand and Why Should I Use It?
Organized By: Statistics SIG
Description
This webinar will introduce estimands, and show how estimands can be used to plan for and address post-randomisation challenges to make the most of PRO data. It will demonstrate how to use this framework to construct, evaluate and communicate PRO estimands using examples from multiple disease areas.
Intended Audience
The intended audience are PRO researchers and clinical trialists, especially those who are non-statisticians.
Level of Knowledge Needed: AdvancedThis webinar will introduce estimands, and show how estimands can be used to plan for and address post-randomisation challenges to make the most of PRO data. It will demonstrate how to use this framework to construct, evaluate and communicate PRO estimands using examples from multiple disease areas.
Intended Audience
The intended audience are PRO researchers and clinical trialists, especially those who are non-statisticians.
Substantial prior training or work experience relevant to the topic is recommended to aid in understanding of webinar content. Strongly suggest attending/viewing webinar 1 of the series.
Audience Benefits
This webinar will provide the audience with:
- An overview of the estimand framework and its relevance in the trial setting
- A clear and accessible demonstration of the value of the estimand framework for patient-reported endpoints, and how these can be applied in the regulatory setting
- A demonstration of how to approach post-randomisation events with estimands
- An understanding of how to interpret estimands for PRO data
- A patient perspective of estimands
At the end of this webinar, attendees will be able to:
- Describe the 5 components of estimands for PROs
- Evaluate the strengths and limitations of different estimand strategies for trials in different clinical areas
- Describe evaluable PRO estimands for a clinical trial
- Understand post-randomisation events and how to plan for them using estimands
- Understand the patient-relevance in applying estimands to evaluate trials
Speakers:
- Libby Floden, PhD MPH, Senior Director, Head of Endpoints, Evinova, United States
- Antoine Regnault, PhD, Partner and Global Lead – Statistics, Modus Outcomes, a Division of THREAD, France
- Rachael Lawrance, BSc, Director and Principal Statistician, Adelphi Values, United Kingdom
- Solomon Alexis, MSc, Principal Lecturer, Head of Collaborative Provisions (TNE), University of East London, United Kingdom
- Jessica Roydhouse, PhD, Select Foundation Senior Research Fellow in Health Services Research, Menzies Institute for Medical Research, University of Tasmania, Australia
Full series details here. Live series is no longer available for purchase.
Recording Policy
Photography, video or audio recording (including screen capture) of ISOQOL courses, sessions, digital materials, or ISOQOL graphics without written permission from ISOQOL is strictly prohibited.
Note that photographs and video recordings taken by or on behalf of ISOQOL is the property of ISOQOL.
*ISOQOL members receive a discounted rate. To view membership rates, click here.