This course will introduce the fundamentals of “Imaging Genetics,” the process of modeling and understanding how genetic variation influences the structure and function of the human brain as measured through brain imaging. The course begins with a brief history of imaging genetics, including discussion on replicability and significance thresholds. Then, we will discuss endophenotypes including modern methods for assessing heritability and genetic correlation. We will cover datasets and methods for conducting common and rare variant associations, as well as bioinformatic tools to interpret significant findings. We will also cover two nascent and related fields: imaging epigenetics and relating gene expression networks to brain structure and function. Overall this course will provide the neuroimager who is not familiar with genetics techniques an understanding of the current state genetics field when exploring neuroimaging phenotypes.