With this issue, PRIM&R is pleased to introduce changes that will make this publication more valuable to our community. We've introduced more animal care and use content, and our Self-Study Program now includes an animal care and use quiz in addition to the human subjects protections quiz, that can be completed to earn continuing education credit. We've also created discussion guides to use for educational or professional development opportunities for IRBs or IACUCs, or to deepen your own understanding of the articles they review.

Articles included:

• Alternative Approaches for Identifying Acute Systemic Toxicity: Moving From Research to Regulatory Testing
• Sex in Context: Limitations of Animal Studies for Addressing Human Sex/Gender Neurobehavioral Health Disparities
• Logical Fallacies in Animal Model Research
• In Vivo Imaging in Pharmaceutical Development and Its Impact on the 3Rs
• Modernizing Biomedical Regulation: Foresight and Values in the Promotion of Responsible Research and Innovation
• Failure of Investigational Drugs in Late-Stage Clinical Development and Publication of Trial Results
• Redefining Responsible Research and Innovation for the Advancement of Biobanking and Biomedical Research
• Ethics and Research with Pregnant Women: Lessons from HIV/AIDS
• Enhancing the Scientific Integrity and Safety of Clinical Trials: Recommendations for Data Monitoring Committees
• Improving the Quality of Informed Consent in Clinical Research with Information Technology
• Evidence-Based Strategies for Shortening Informed Consent Forms in Clinical Research
• A Randomized Study of a Method for Optimizing Adolescent Assent to Biomedical Research
• Enhanced REC Collaborative Review Through Videoconferencing
• A Case Study of Researchers’ Knowledge and Opinions about the Ethical Review Process for Research in Botswana

PRIM&R’s Research Ethics Digest, an electronic publication, delivers timely and relevant abstracts and full-text articles from a wide array of scholarly journals to the inboxes of PRIM&R members every two months. Articles featured in Research Ethics Digest highlight new research and scholarship related to ethics and regulation that affect—and potentially enhance—daily work.

The Research Ethics Digest Self-Study Program allows PRIM&R members to earn continuing education credits, which can be applied toward their Certified IRB Professional (CIP^®) credential, Certified Professional in IACUC Administration (CPIA^®) credential recertification, or other professional credentials they may hold.