The articles included in this month’s issue of Research Ethics Digest offer new discussion of challenging and controversial topics related to research ethics, including studies of strategies for improving the efficiency of IRBs, analysis of new informed consent protocols, reviews of ethical hurdles for health systems research, and further topics.

Articles included:

• Conduct, Oversight, and Ethical Considerations of Clinical Trials in Companion Animals with Cancer: Report of a Workshop on Best Practice Recommendations
• Transparency and Public Involvement in Animal Research
• Establishing the First Institutional Animal Care and Use Committee in Egypt
• Ethical Issues in Using Twitter for Population-Level Depression Monitoring: A Qualitative Study
• Research Ethics Committees and Participatory Action Research With Young People: The Politics of Voice
• Ethical Challenges in Designing and Implementing Health Systems Research: Experiences From the Field
• Citizen Science or Scientific Citizenship? Disentangling the Uses of Public Engagement Rhetoric in National Research Initiatives
• Clearing Complexity from the Common Rule NPRM
• CRISPR-Cas9 and the Non-Germline Non-Controversy
• The Ethics of Large-Scale Genomic Research
• A Pilot Study of Universities' Willingness to Solicit Whistleblowers for Participation in a Study
• When and Why Is Research Without Consent Permissible?
• Improved Participants' Understanding in a Healthy Volunteer Study Using the SIDCER Informed Consent Form: A Randomized-Controlled Study
• SIDCER Informed Consent Form: Principles and a Developmental Guideline
• Prevalence and Commonalities of Informed Consent Templates for Biomedical Research
• Time Required to Review Research Protocols at 10 Veterans Affairs Institutional Review Boards
• Evolving the IRB: Building Robust Review for Industry Research
• Impact of the Pediatric Central Institutional Review Board in Children's Oncology Group Phase 1 Consortium Dose Escalation Studies
• Prioritizing Initiatives for Institutional Review Board Quality Improvement
• Variation in University Research Ethics Review: Reflections Following an Inter-University Study in England
• Small is Beautiful: Demystifying and Simplifying Standard Operating Procedures: A Model from the Ethics Review and Consultancy Committee of the Cameroon Bioethics Initiative
• Study Partners Perform Essential Tasks in Dementia Research and Can Experience Burdens and Benefits in This Role
• The National Children's Study: Recruitment Outcomes Using the Provider-Based Recruitment Approach
• Ethical Considerations of Conducting Research Among Children and Young People Affected by HIV: A View from an Ethics Review Board

PRIM&R’s Research Ethics Digest, an electronic publication, delivers timely and relevant abstracts and full-text articles from a wide array of scholarly journals to the inboxes of PRIM&R members every two months. Articles featured in Research Ethics Digest highlight new research and scholarship related to ethics and regulation that affect—and potentially enhance—daily work.

The Research Ethics Digest Self-Study Program allows PRIM&R members to earn continuing education credits, which can be applied toward their Certified IRB Professional (CIP®) credential, Certified Professional in IACUC Administration (CPIA®) credential recertification, or other professional credentials they may hold.