For decades, researchers have inserted different types of human cells into nonhuman animals at various stages of development to advance our understanding of human biological processes and identify new investigational therapies.
When these studies involve the transfer of human stem cells (or their direct derivatives), they tend to raise questions such as whether the moral status of nonhuman animals is altered by the insertion of human stem cells, whether it is morally appropriate to cross species boundaries in this way, and whether these studies should be subject to additional prohibitions or oversight beyond that generally imposed on research involving somatic cells donated by human subjects and research with nonhuman animals.
Consequently, stem cell-based chimeric research has been surrounded by cross-disciplinary debate about whether such scientific work should take place and how best to respond to the ethical and policy issues it raises.
In this session, we will provide an overview of the debate and regulatory issues in chimeric research and discuss one or two illustrative case studies that identify challenges for IRB, IACUC, and ESCRO professionals. Discussion will focus on ways to improve oversight, and speakers will address questions from participants. Time will also be devoted to answering attendee questions.
What will I learn?
- Define chimeric research
- Identify several ethical and policy issues raised by this research
- Identify several oversight challenges
- Describe some suggestions for improving oversight
Who should attend?
Members and support staff for ESCRO committees, IACUCs and IRBs; oversight professionals/research administrators.
Continuing Education Credit
Course participants who hold the Certified Professional in IACUC Administration (CPIA®) credential may apply 1.25 continuing education credits towards CPIA recertification category two credit. Learn More
Webinar participants holding the Certified IRB Professional (CIP®) credential may apply 1.25 continuing education credits towards CIP recertification. Learn More
Access Interval
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