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Webinar: (09-22) Chimeras (But Don't Call Them Chimeras): An Introduction to the Ethics and Policy Debate

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Description

For decades, researchers have inserted different types of human cells into nonhuman animals at various stages of development to advance our understanding of human biological processes and identify new investigational therapies.

When these studies involve the transfer of human stem cells (or their direct derivatives), they tend to raise questions such as whether the moral status of nonhuman animals is altered by the insertion of human stem cells, whether it is morally appropriate to cross species boundaries in this way, and whether these studies should be subject to additional prohibitions or oversight beyond that generally imposed on research involving somatic cells donated by human subjects and research with nonhuman animals.

Consequently, stem cell-based chimeric research has been surrounded by cross-disciplinary debate about whether such scientific work should take place and how best to respond to the ethical and policy issues it raises.

In this session, we will provide an overview of the debate and regulatory issues in chimeric research and discuss one or two illustrative case studies that identify challenges for IRB, IACUC, and ESCRO professionals. Discussion will focus on ways to improve oversight, and speakers will address questions from participants. Time will also be devoted to answering attendee questions.


What will I learn?
  • Define chimeric research
  • Identify several ethical and policy issues raised by this research
  • Identify several oversight challenges
  • Describe some suggestions for improving oversight 

Who should attend?
Members and support staff for ESCRO committees, IACUCs and IRBs; oversight professionals/research administrators.

Continuing Education Credit

Course participants who hold the Certified Professional in IACUC Administration (CPIA®) credential may apply 1.25 continuing education credits towards CPIA recertification category two credit. Learn More

Webinar participants holding the Certified IRB Professional (CIP®) credential may apply 1.25 continuing education credits towards CIP recertification. Learn More

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Contributors

  • Josephine M. Johnston, LLB, MBHL

    Josephine Johnston is Director of Research and a Research Scholar at The Hastings Center, an independent bioethics research institute in Garrison, New York. She works on the ethics of emerging biotechnologies, particularly as used in human reproduction, psychiatry, genetics, and neuroscience. Her scholarly work has appeared in medical, scientific, policy, law, and bioethics journals, including New England Journal of Medicine, Science, Nature, Hastings Center Report, and Journal of Law, Medicine and Ethics. She is co-editor of Human Flourishing in an Age of Gene Editing (Oxford University Press, 2019) and Trust and Integrity in Biomedical Research: The Case of Financial Conflicts of Interest (Johns Hopkins University Press, 2010). Ms. Johnston holds degrees in law and bioethics from the University of Otago in New Zealand.

  • Insoo Hyun, PhD

    Insoo Hyun is Director of Research Ethics and a faculty member of the Center for Bioethics and senior lecturer on Global Health and Social Medicine at Harvard Medical School. He is also Professor of Bioethics and Philosophy at Case Western Reserve University School of Medicine. As a Fulbright Scholar and Hastings Center Fellow, Dr. Hyun's interests include ethical and policy issues in stem cell research and new biotechnologies.

    Dr. Hyun has been involved for many years with the ISSCR (International Society for Stem Cell Research). He has helped draft all of the ISSCR’s international research guidelines and is the current Chair of the ISSCR Ethics Committee.

    Dr. Hyun received his BA and MA in Philosophy with Honors in Ethics in Society from Stanford University and his PhD in Philosophy from Brown University. He has been interviewed frequently on National Public Radio and has served on national commissions for the Institute of Medicine and the National Academy of Sciences in Washington D.C. Dr. Hyun is a regular contributor to Nature, Science, Cell Stem Cell, The Hastings Center Report, among many other journals.

September 15, 2022
Thu 1:00 PM EDT

Duration 1H 15M

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