A Series of CME-certified, MOC-eligible Live Webinars
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DATE AND TIME
Saturday, January 23, 2021
10:00 - 11:00 AM ET (9:00 - 10:00 AM CT / 7:00 - 8:00 AM PT)
Hosted by: Alabama Society of Allergy, Asthma, and Immunology
Welcome and Introductions
Pathogenesis of Asthma
Ensuring Timely and Accurate Diagnoses of Severe Asthma
Targeted Approach to Controlling Asthma Based on Phenotype and Severity
Patient Engagement and Strategies to Improve Adherence
Q&A Session and Activity Roundup
Patients with severe, persistent asthma (~4%-10% of all asthma cases) are managed by Global Initiative for Asthma (GINA) steps 4 or 5. These guidelines recommend a phenotypic assessment and selection of additional treatment based on the results of testing. This activity, “Asthma Management in the Era of Targeted Therapy: Using Phenotype and Biomarkers to Individualize Management,” will help allergists, immunologists, and other clinicians to diagnose severe asthma, use clinical presentation and biomarker results to determine asthma phenotype, and use this information to develop appropriate individualized management plans for their patients with severe asthma.
Professor of Pediatrics
Director - Center for Pediatric Asthma Research
Scientific Director - Center for Clinical and Translational Research
Monroe Carell Jr. Children’s Hospital at Vanderbilt University Medical Center
Leonard B. Bacharier, MD MD is the Professor of Pediatrics, Director of the Center for Pediatric Asthma Research and Scientific Director of the Center for Clinical and Translational Research at Monroe Carell Jr. Children’s Hospital at Vanderbilt University Medical Center in Nashville, TN. His research focuses on childhood asthma and he is an investigator for several National Institutes of Health (NIH)-funded asthma programs, including AsthmaNet, the Inner City Asthma Consortium, and PrecISE.
Dr. Bacharier is currently investigating the role of early infection with respiratory syncytial virus upon the subsequent development of asthma. He serves as an Associate Editor for the Journal of Allergy and Clinical Immunology, as a member of the Global Initiative for Asthma (GINA) Science Committee, and as Chair of the American Board of Allergy and Immunology.
Wanda Phipatanakul, MD, MS
Professor of Pediatrics
Harvard Medical School
Director, Asthma Clinical Research Center
Boston Children's Hospital
Wanda Phipatanakul, MD, MS is Director of the Asthma Clinical Research Center at Boston Children’s Hospital and Professor of Pediatrics at Harvard Medical School. She has dedicated her career to reducing and preventing asthma and allergic diseases.
Originally from St. Louis, she earned her medical degree from Loma Linda University and completed her residency in pediatrics at Children’s Hospital Los Angeles in 1997. After a fellowship in immunology at Johns Hopkins University, she joined the faculty in the Division of Immunology and Allergy at Boston Children’s and Harvard Medical School, where she has remained for the past 19 years.
Dr. Phipatanakul has built a deep network of community relationships and conducts both school- and home-based asthma studies in children. She has also had continuous National Institutes of Health (NIH) funding for nearly 20 years. She leads the National Institute of Allergy and Infectious Diseases (NIAID) School Inner-City Asthma Intervention Study and the National Heart, Lung, and Blood Institute (NHLBI) Environment Assessment of Sleep in Youth. She is the overall Principal Investigator for an NIAID-funded, nationwide, multicenter asthma-prevention study evaluating omalizumab (anti-IgE) in preventing the atopic march and asthma.
Most recently, Dr. Phipatanakul was awarded an NIAID U01 evaluating whether patients carrying an IL4RαR576 gene variant will have a greater response to dupilumab. She leads her Center as Pediatric PI in multiple NHLBI asthma and prevention networks, including Precise, and has authored more than 220 publications in scientific journals, including JAMA and the New England Journal of Medicine. She is passionate about successfully mentoring the next generation of investigators, serving the American Academy of Allergy, Asthma & Immunology (AAAAI) and the American Board of Allergy and Immunology (ABAI) in support of her specialty, and serving as a role model to others balancing work and family.
This activity is intended for allergists, immunologists, and other clinicians involved in the diagnosis and treatment of patients with severe asthma.
This program is designed to address ACGME and NAM competencies, including delivering patient-centered care and practicing evidence-based medicine.
At the conclusion of this activity, participants should be able to:
Use a patient’s clinical presentation and predictive biomarkers to determine asthma phenotype Identify patients with severe asthma using the latest guideline recommendations Differentiate among the various subtypes (e.g. eosinophilic), and phenotypes or endotypes of asthma Develop personalized management plans incorporating clinical phenotype, biomarkers, and the mechanism of action, efficacy, and safety profiles of available pharmacologic and biologic agents Incorporate strategies to engage patients in their care, improving disease understanding and adherence to treatment
This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of Boston University School of Medicine and Rockpointe. Boston University School of Medicine is accredited by the ACCME to provide continuing medical education for physicians.
Boston University School of Medicine designates this live activity for a maximum of 1.00 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
AMERICAN BOARD OF ALLERGY AND IMMUNOLOGY (ABAI) MOC POINTS
Diplomates of the American Board of Allergy and Immunology (ABAI) must attest to obtaining 25 hours of Allergy/Immunology-specific CME credits from accredited organizations every year in order to fulfill the lifelong learning component of MOC. Participation in this activity will support board certified allergists and immunologists in contributing towards this MOC requirement set forth by the ABAI.
These materials and all other materials provided in conjunction with continuing medical education activities are intended solely for purposes of supplementing continuing medical education programs for qualified health care professionals. Anyone using the materials assumes full responsibility and all risk for their appropriate use. Trustees of Boston University makes no warranties or representations whatsoever regarding the accuracy, completeness, currentness, noninfringement, merchantability or fitness for a particular purpose of the materials. In no event will trustees of Boston University be liable to anyone for any decision made or action take in reliance on the materials. In no event should the information in the materials be used as a substitute for professional care.
This educational activity has been produced in adherence with the policies and guidelines, including the Standards for Commercial Support, set forth to providers by the Accreditation Council for Continuing Medical Education (ACCME) and all other professional organizations, as applicable, stating those activities where continuing education credits are awarded must be balanced, independent, objective, and scientifically rigorous.
Boston University School of Medicine asks all individuals, and their spouses/partners, involved in the development and presentation of Continuing Medical Education (CME) and Continuing Nursing Education (CNE) activities to disclose all relevant financial relationships with commercial interests. This information is disclosed to CME activity participants prior to the start of the educational activity. Boston University School of Medicine has procedures to resolve all conflicts of interest. In addition, faculty members are asked to disclose when any unapproved use of pharmaceuticals and devices is being discussed.
The faculty and steering committee reported the following relevant financial relationships that they or their spouse/partner have with commercial interests:
Leonard B. Bacharier, MD: Consultant: Aerocrine, AstraZeneca, Boehringer Ingelheim, Genentech/Novartis, GlaxoSmithKline, Sanofi/Regeneron, Teva; Speaker: AstraZeneca, GlaxoSmithKline, Novartis, Sanofi/Regeneron; Advisory Board: Circassia, Merck, Sanofi/Regeneron, Vectura; Data Safety Monitoring Board: DBV Technologies
Wanda Phipatanakul, MD, MS: Grant/Research Consultant: Genentech, Novartis, Regeneron, Sanofi
Hasmeena Kathuria, MD, BUSM CME Course Director: Nothing to disclose
NON-FACULTY CONTENT CONTRIBUTORS
Non-faculty content contributors and/or reviewers reported the following relevant financial relationships that they or their spouse/partner have with commercial interests:
Terry Ann Glauser, MD, MPH; Blair St. Amand; Elizabeth Drury; Natalie Sanfratello, MPH: Nothing to disclose
The contents of some CME/CE activities may contain discussions of non-approved or off-label uses of some agents mentioned. Please consult the prescribing information for full disclosure of a
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INSTRUCTIONS FOR PARTICIPANTS AND OBTAINING CME CREDIT
There is no fee for this activity. To receive credit, participants must register, view the live CME activity in its entirety, and then complete the post-test with a score of 70% or better and the evaluation. The estimated time for completion of this activity is 1 hour. To receive a certific
Jointly provided by Boston University School of Medicine and Rockpointe