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Management of Neovascular Age-Related Macular Degeneration: Improving Patient Outcomes

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    May 28, 2020
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    • The avatar for the contributor named Jennifer I. Lim, MD, FARVO. Jennifer I. Lim, MD, FARVO
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    October 07, 2020
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    • The avatar for the contributor named Jennifer I. Lim, MD, FARVO. Jennifer I. Lim, MD, FARVO
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Contributors

  • Jennifer I. Lim, MD, FARVO

    Marion H. Schenk Chair
    Professor of Ophthalmology
    Director of the Retina Service
    University of Illinois at Chicago
    Chicago, IL

    Jennifer I. Lim, MD, FARVO holds the Marion H. Schenk Chair in Ophthalmology for Research in the Aging Eye as a Professor of Ophthalmology and Director of the Retina Service at the University of Illinois at Chicago. Her areas of expertise include surgical and medical retinal diseases. She received her medical doctorate with distinction from Northwestern University, where she received both the Dean’s AOA Student Research Award and the Julius Conn Memorial Award. She completed her ophthalmology training at University of Illinois at Chicago, receiving the Resident Research Award and the American College of Surgeons Resident Competition Chicago Chapter Keeshin Prize.

    She completed medical and surgical retina fellowships at the Wilmer Eye Institute of Johns Hopkins Hospital, where she was a Heed Fellow and a Heed Knapp Fellow Awardee. After completing her training, she joined the faculty of Emory University as an Assistant Professor of Ophthalmology. She was recruited to Doheny Eye Institute of University of Southern California as an Associate Professor with tenure and then promoted to Professor of Ophthalmology. In 2007, she was recruited to University of Illinois at Chicago as the Director of the Retina Service.

    Her research interests include clinical trials, translational research, and retinal vascular disease. She has been principal investigator for more than 60 clinical trials. She collaborates with basic scientists on angiogenesis and imaging research and has received funding from the National Eye Institute, Macula Society Research Fund, American Cancer Society, and numerous industry grants. Her current leadership positions include Deputy Associate Editor for JAMA Ophthalmology, EyeWiki Retina Section Editor, Treasurer of the Retina Society, Chair of the Nominating Committee of Macula Society, and Vice President of the Chicago Ophthalmology Society. She serves as an Associate Examiner of the American Board of Ophthalmology (ABO) and has served on the Maintenance of Certification Committee of the AAO.

    Among numerous honors, she has received the AAO Lifetime Achievement Award (2018), ARVO Gold Fellow Award (2019), Silver Fellow Award (2014), and Mother McAuley Liberal Arts High School Hall of Honor (2019). She was the inaugural University of Illinois at Chicago Distinguished Sweeney Lecturer and was named to Chicago Super Docs, Best Doctors in America, Top Doctors, and the ASRS Retina Hall of Fame (charter inductee). She has authored or co-authored more than 300 articles and 30 book chapters and edited several books, including Age-Related Macular Degeneration, which is currently in its Third Edition.

  • Quan Dong Nguyen, MD, MSc

    Professor of Ophthalmology
    Byers Eye Institute
    Spencer Center for Vision Research
    Wu Tai Neurosciences Institute
    Stanford University School of Medicine
    Stanford, CA

    Quan Dong Nguyen, MD, MSc was born in Saigon, Vietnam, and immigrated with his parents and three brothers to the United States in 1980. He is currently Professor of Ophthalmology at the Byers Eye Institute at Stanford University School of Medicine.

    After completing his education at the Phillips Exeter Academy, Yale, University of Pennsylvania, and Harvard in 2001, Dr. Nguyen joined the faculty at the Wilmer Eye Institute at Johns Hopkins as Assistant Professor and then Associate Professor of Ophthalmology and Director of Medical Education. In 2013, he was appointed as the McGaw Endowed Chair in Ophthalmology, Professor and Chairman of the Department of Ophthalmology, and the Inaugural Director of the Stanley M. Truhlsen Eye Institute, as well as Assistant Dean for Translational Research at the University of Nebraska Medical Center.

    Dr. Nguyen is the principal investigator for multiple clinical trials sponsored by the National Eye Institute and other organizations on macular edema (from diabetes and uveitis), neovascular age-related macular degeneration (AMD), and ocular inflammatory and uveitic diseases. Dr. Nguyen is known for his innovative work in early proof-of-concept, first-in-human clinical trials to evaluate potential pharmacotherapeutic agents for retinal vascular and uveitic diseases. He and his team were among the first scientists in the world to evaluate aflibercept for neovascular AMD and ranibizumab for diabetic macular edema (DME); the initial results of these studies served as the foundation for subsequent trials leading to the approval of these pharmacologic agents by the FDA and other regulatory authorities for the indicated diseases. Dr. Nguyen has chaired the US multi-center READ-2, READ-3, and iDEAL studies, evaluating the potential role of VEGF antagonists through different pathways for DME.

    Dr. Nguyen led the SAVE and multi-centered SAVE-2 and STOP-UVEITIS studies to evaluate the role of new pharmacologic agents, including specific interleukin inhibition in uveitis and ocular inflammatory diseases. Throughout his career, Dr. Nguyen has shared his scientific work through numerous manuscripts published in the literature. He serves on the Editorial Board of several journals, including the Journal of Ophthalmic Infection and Inflammation and Ophthalmic Surgery, Laser, and Imaging – Retina, among others.

    At the Byers Eye Institute at Stanford, Dr. Nguyen has an active practice for uveitis and ocular inflammatory diseases, as well as clinical and surgical retina procedures, while he continues his research in pharmacotherapy and ocular imaging. In addition, he teaches and trains students, residents, and fellows from the United States and around the world.

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