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MALDI-TOF-MS sample preparation – introducing an enabling pipetting technology

Description

Matrix Assisted Laser Desorption Ionization Time of Flight Mass Spectrometry MALDITOF- MS) has been recently developed and calls for novel approaches in the design of automated liquid handling systems. In this discussion, we provide an overview of application demands for a reliable sample preparation automation – from a small and easy-to-use workstation to a fully automated integration solution by Analytik Jena. We highlight the challenges that need to be overcome to improve the lab process including the liquid handling leading to an increased quality of your results. We present an outlook to further fields of applications possible with our systems such as SAMDI, biotyping, screening etc. In addition, we provide guidelines for selecting a suitable system for MALDI-TOF-MS sample preparation.

Key learning objectives:
- Advantages of laboratory automation workflows
- Challenges during the optimization of automated MALDI-TOF sample preparation
- How to successfully overcome hardware, software and labware challenges
- Recommendations in optimization of liquid handling parameters

FREE for SLAS Members


Contributors

  • Dr. Matthias Fischer, Team Leader Automation, Analytik Jena AG

    Matthias Fischer has a background in biomedical engineering, obtained in 2007 from the University of Applied Sciences, Jena, Germany. While completing his Ph.D. at the GEOMAR Helmholtz Centre for Ocean Research Kiel in Germany, he developed a fluorescence-based fiber-optical biofilm sensor
    for studying biofilm formation dynamics in the field. In 2013, he joined the photonics group at the University of York, United Kingdom, as a postdoctoral researcher. Since 2017 Dr. Fischer's focuses on the design and development of lab automation systems to address liquid handling applications.

November 5, 2020
Thu 7:00 AM CST

Duration 1H 0M

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