Researchers focused on the
pharmacogenetics of nicotine addiction treatment have conducted multiple
studies that have contributed to an evidence base that will allow individuals
and providers to select which medication would be the most optimal for smoking
cessation. In this seminar, Dr. Caryn Lerman (USC, USA) discusses the history of precision
therapy and the process model that is used to iteratively inform the future use
of this treatment. An introduction and summary discussion are provided by Robert Schnoll, PhD (University of Pennsylvania, USA).
By completing this seminar, the learners will:
- Gain a good understanding of previous research that has led to the development of precision therapy via nicotine metabolism
- Learn how nicotine metabolism rate (NMR) is measured
- Understand how NMR may be used to tailoring treatments (e.g., nicotine replacement therapy vs non-nicotine therapies)
- Appreciate the difference in efficacy of precision therapy in clinical trials versus real world applications
- Comprehend the process model for precision therapy, including the challenges in how to proceed with future research.