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SC62 Part 2 - Algorithmic Approach to Diagnosis of Inflammatory Disorders of the GI Tract

Faculty: Amitabh Srivastava, MD, and Robert D. Odze, MD, Brigham and Womens Hospital, Boston, MA and Gregory Y. Lauwers, MD, Massachusetts General Hospital, Boston, MA
The standard approach in teaching inflammatory disorders of the GI tract is to describe clinical and histologic features of individual diseases entities. This is, however, not the best method of establishing diagnoses when practicing pathology at the microscope, where a constellation of clinical, endoscopic, and histologic features must be analyzed and incorporated into a specific diagnosis. Common inflammatory disorders, such as Barrett's esophagus and inflammatory bowel disease, lead to lifelong surveillance and impose a significant burden on the patients and on health care costs. Accurate and unambiguous diagnosis is, therefore, critical for optimal patient management.
This course will cover six of the most common and diagnostically challenging areas of inflammatory disorders involving the GI tract including squamous esophagitis, GE junction biopsies, acute and chronic gastritis, upper and lower intestinal biopsies with inflammation ("enteritis"), and acute and chronic colitis. Most of the common, and selected rare inflammatory disorders, will be covered within the context of diagnostic algorithms specific to each site. The course will be useful for general surgical pathologists, trainees (residents/fellows) in pathology, and for subspecialty GI pathologists interested in novel educational tools for their residents and fellows.
Upon completion of this educational activity, participants should:
  • Understand and execute an algorithmic approach to diagnosis of common inflammatory disorders of the GI tract
  • Understand the clinical importance and relevance of using standardized nomenclature in diagnosis of mucosal biopsy specimens
  • Understand the major histologic features that help differentiate clinically and endoscopically similar inflammatory disorders of the GI tract
  • Understand common diagnostic pitfalls in non-neoplastic gastrointestinal pathology and how they may have a major impact on patient management.

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