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SC51 - High Yield Urological Pathology: Common and Important Diagnoses Not To Be Missed in Daily Practice



Evaluated by: Laura W. Lamps, M.D., UAMS Health, July 8, 2016 
Original release date: March 18, 2016
Access to this course expires on: March 18, 2019
CME/SAMs 3.0

Course Description
Urologic pathology specimens constitute a significant portion of surgical pathologists daily work. There are numerous urologic diseases and neoplastic conditions that are histologically similar but have distinct clinical and therapeutic implications. Their correct diagnosis and classification are critical but often pose a significant challenge to surgical pathologists. Rather than reviewing general GU topics, the faculty of this short course have identified common diagnostic difficulties in GU pathology that surgical pathologists grapple with in daily sign-out based on their subspecialty sign-out and consultation experience.

Target Audience
Practicing academic and community pathologists, and pathologists-in-training

Learning Objectives
Upon completion of this educational activity, learners will be able to:

  • Resolving atypical glandular lesions in prostate biopsies using an integrated morphological and immunohistochemical approach;
  • Common yet challenging benign mimics of prostate cancer and prostate cancer variants that mimic benign
  • Differential diagnosis and implications of atypical cribriform lesions in prostate biopsy
  • Contemporary Gleason grading scheme
  • Diagnostic algorithm for urothelial lesions with endophytic growth pattern
  • Benign mimickers of urothelial carcinoma
  • Morphological variants of urothelial cancer in TURBT biopsies
  • An approach to resolving difficult staging related issues in transurethral bladder resections
  • New and emerging renal cell carcinoma histological subtypes
  • Update on staging of renal cell carcinomas
  • Diagnosis of renal tumors on needle biopsy.
  • Apply updated Gleason grading system
  • Use a pattern-based approach and algorithms in the diagnosis and differential diagnosis of urological neoplasms
  • Recognize new and emerging histological subtypes of renal epithelial neoplasms
  • Judicious use of immunohistochemical markers in the work-up of urological diseases
Discussion will focus on the morphological clues to diagnosis and differential diagnosis, judicious use of immunohistochemistry, clinical implications and take-home messages. The course is designed for advanced residents and general pathologists, as well as subspecialists in urological pathology.

The United States and Canadian Academy of Pathology is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

The United States and Canadian Academy of Pathology designates this enduring material for a maximum of 3 AMA PRA Category 1 CreditsTM. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

The USCAP is approved by the American Board of Pathology (ABP) to offer Self-Assessment credits (SAMs) for the purpose of meeting the ABP requirements for Maintenance of Certification (MOC). Registrants must take and pass the post-test in order to claim SAMs credit.

Physicians can earn a maximum of 3 SAM credit hours.

The faculty, committee members, and staff who are in position to control the content of this activity are required to disclose to USCAP and to learners any relevant financial relationship(s) of the individual or spouse/partner that have occurred within the last 12 months with any commercial interest(s) whose products or services are related to the CME content. USCAP has reviewed all disclosures and resolved or managed all identified conflicts of interest, as applicable.

The following faculty reported no relevant financial relationships: Ming Zhou, MD, PhD, New York University Medical Center, New York, NY ; Kiril Trpkov, MD, University of Calgary, Calgary, AB and Rajal B. Shah, MD, Miraca Life Sciences, Irving, TX

USCAP staff associated with the development of content for this activity reported no relevant financial relationships.



To earn CME and SAM credit, all learners must take a content-based exam and achieve a minimum score of 80%. If learners do not achieve a passing score of 80%, they have the option to retake the exam. After you pass the test and complete the evaluation, your certificate of completion will be available to view and print by clicking here.

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