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Hepatocellular Carcinoma, Metastases and Mimics, Oh My

CME 0.75 / 0.75 SAMs

November 27, 2016 by David B. Kaminsky, M.D., FIAC
Available for CME credit through November 26, 2019

This lecture will focus on tumors involving the liver. The liver is a common site for many different tumors. At times, it can be difficult to determine whether well differentiated hepatocellular lesions represent reactive liver, benign tumors or malignant tumors.Furthermore, hepatocellular carcinoma can be confused with metastatic adenocarcinoma from multiple different sites. I will review common pitfalls and challenges in the diagnosis of tumors in the liver. In addition, I will update the audience as to the most currently useful immunohistochemical stains for the differential of tumors in the liver.

Intended Audience:
Our intended audience includes practicing pathologists, pathology residents and fellows.

Topics Covered:
  • Approach to the evaluation of liver tumors
  • Well differentiated hepatocellular neoplasms
  • Hepatocellular carcinoma and metastatic adenocarcinoma to the liver
  • Mimics and pitfalls in the diagnosis of tumors in the liver

Upon completion of this educational activity, the participants should be able to:
  • Develop a practical approach to the evaluation of tumors in the liver
  • Know the differential for tumors in a non-cirrhotic liver, and the distinction between hepatic adenoma, focal nodular hyperplasia, and hepatocellular carcinoma
  • Determine the most useful immunohistochemical work-up to distinguish hepatocellular carcinoma from metastases and mimics

Handouts are located in Resources tab

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