Why Are Small Airways Important in Asthma?

Why Are Small Airways Important in Asthma?

A WAO Symposium presented by members of the WAO Small Airways Working Group during the XXII World Allergy Congress (WAC 2011) in Cancun, Mexico, 7 December 2011.

Welcoming Remarks by the Chairpersons
LANNY ROSENWASSER:
Dee Lyons/Missouri Endowed Chair in Pediatric Immunology Research; Professor of Pediatrics, Allergy-Immunology Division, Children's Mercy Hospital; Professor of Pediatrics, Medicine, and Basic Science; University of Missouri-Kansas City School of Medicine, USA
J. CHRISTIAN VIRCHOW:
Head, Department of Pneumology; Intensive Care Medicine Zentrum f. Innere Medizin; Klinik I; University Clinic Rostock, Germany



Pathophysiology of Small Airways Disease
Presented by: Quatayba Hamid
Professor of Medicine, McGill University
Director, Meakins-Christie Laboratories
Associate Director, McGill University Health Centre Research Institute
Montreal, Quebec, Canada

Learning Objectives:

  1. Update the audience/participants with unlimited knowledge on the role of Severe Asthma in asthmatics
  2. Explore different pathways that might be of interest of new therapeutic approach

Physiology of Small Airways Disease
Presented by: Charles Irvin
Professor, Department of Molecular Physiology & Biophysics and Department of
edicine, University of Vermont College of Medicine
Director, Vermont Lung Center
Colchester, Vermont, USA

Learning Objectives:

  1. Understand the structural basis of small airways resistance and the “silent zone" of the lung
  2. Discuss the pathogenesis and patho-physiological mechanisms of small airways diseases
  3. Understand the relationship of small airways disease to AHR and symptoms of asthma
  4. Appreciate the pattern PFT results that suggest small airways dysfunction

Particle Deposition and Pharmacotherapy of Small Airways Disease
Presented by: Lanny Rosenwasser
Dee Lyons/Missouri Endowed Chair in Pediatric Immunology Research
Professor of Pediatrics, Allergy-Immunology Division, Children's Mercy Hospital
Professor of Pediatrics, Medicine, and Basic Science
University of Missouri-Kansas City School of Medicine, USA

Learning Objectives:

  1. Understand the concept of particle deposition
  2. Understand how particle size impacts deposition of inhaled asthma medications
  3. Understand the relationship of particle size and deposition to physiologic responses of small airways
Handouts
Handouts for this session are available from the WAC 2011 scientific program online.

Additional resources of the WAO Small Airways Working Group, including a small airways scientific literature database, are available online.



This WAO Symposium and the video recording of it was supported through an unrestricted educational grant from Teva.





This WAO Symposium was also supported through an unrestricted educational grant from Takeda.





WAO Contact Information
World Allergy Organization
555 East Wells Street, Suite 1100
Milwaukee, Wisconsin 53202-3823 USA
Phone: +1-414-276-1791 Fax: +1-414-276-3349
E-mail:info@worldallergy.org
Internet: www.worldallergy.org