The majority of patients afflicted with glaucoma live in the developing world, where medical treatment is impractical. How should we address the global burden of the disease, and can we design a process that is practical and self-sustaining? Can we help those impaired or nearly blind from the disease? Can we identify those most likely to deteriorate rapidly and focus our attention on them? Can we create a mobile medical record so that each new glaucoma provider gets a longer-term view of the patient’s history? Is neuro-protective treatment feasible in the near term? This Symposium will focus on the many unmet needs of interest to the wider glaucoma community.