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S23 Challenges of medical therapy

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Description

Individualized glaucoma treatment aims at providing glaucoma management tailored to the individual needs of the patient; patients with severe functional loss or younger patients with manifest disease should have more aggressive treatment and closer follow-up than patients with little or no risk, e.g. patients with ocular hypertension (or elevated IOP) and otherwise normal findings, or elderly patients with mild field loss and low IOP levels. Many patients however are still unable or unwilling to follow the therapeutic regimen, or do not respond favorably. This symposium focuses on some of the possible ways to improve the efficacy of medical treatment, like new mechanisms of IOP lowering, the therapeutical effects of drugs beyond IOP lowering, new delivery systems, iatrogenic disturbances of the ocular suface and last but not least the impact of compliance on glaucoma treatment.

Contributors

  • Robert Ritch, MD

    Affiliation: Shelley and Steven Einhorn Distinguished Chair in Ophthalmology; Surgeon Director and Chief of Glaucoma Services at the New York Eye and Ear Infirmary, New York City; Professor of Ophthalmology at The New York Medical College, Valhalla, NY.

    Areas of Interest: The understanding of the nature of glaucoma and innovation in the medical, laser, and surgical treatment of glaucoma.

    Positions: Diplomate, American Board of Ophthalmology; Fellow, American Academy of Ophthalmology, American College of Surgeons, International College of Surgeons, Royal College of Ophthalmology, ARVO, and member of Academia Ophthalmologica Internationalis. President of the Ophthalmic Laser Surgical Society, the New York Glaucoma Society, the Section on Ophthalmology of the New York Academy of Medicine, and the New York Society for Clinical Ophthalmology and Vice-President of ARVO. He serves on numerous medical and scientific advisory and editorial boards. He has co-authored or edited nine textbooks and over 1600 medical and scientific papers, book chapters, articles and abstracts. He has presented over 700 lectures worldwide, including 40 named lectures. In 1985, he founded the Glaucoma Foundation. Dr. Ritch has trained nearly 140 clinical and research fellows, many of whom occupy academic positions worldwide, and 60 International Council of Ophthalmology fellows and over 100 observers from over 50 countries. He has worked and lectured extensively at the international level and has organized many symposia and conferences. He founded the International Teaching Consortium and has organized meetings, established teaching programs and helped to modernize ophthalmology in Thailand, Malaysia, the Philippines, Laos, Myanmar and other countries in Asia.

    Special Honors: Among his awards since 2006 are the Albion O. Bernstein, MD Award for outstanding contributions to medicine, the American Academy of Ophthalmology Lifetime Achievement Honor Award, the Leadership in Education in Ophthalmology (LEO) Award, the TKC Liu Memorial Award for Leadership in Ophthalmology, the Dominick Purpura Distinguished Alumnus Annual Award from Albert Einstein College of Medicine, the ARVO Distinguished Service Award, ARVO Gold Fellowship, the HRH Prince Abdulaziz Al-Saud Prevention of Blindness Award, the Jose Rizal International Medal, The Asia-Pacific Academy of Ophthalmology Achievement Award, the El-Maghraby International Award, the Inaugural Asia-Pacific Glaucoma Society International Award, and the 2013 Honoree of the American Glaucoma Society.

  • Carlo Enrico Traverso, MD

    Affiliation: Director of Clinica Oculistica, Department of Neurosciences, Ophthalmology and genetics (Di.N.O.G.), University of Genova; Director, Residency program in Ophthalmology, depart ment of Neurosciences, Ophthalmology and genetics (Di.N.O.G.), University of Genova, Italy

    Leadership Position: Department of Neurosciences, Ophthalmology and Genetics (Di.N.O.G.), University of Genova; Medical Director, Eye Bank of Genova - Fondazione Melvin Jones Lions; President, European Glaucoma Society (EGS) since 2010; Coordinator and founder, Clinical Research Center and laboratory for Glaucoma and Cornea, Department of Neurosciences, Ophthalmology and Genetics (Di.N.O.G.), University of Genova, since 2006; Coordinator, Regional Center for Biological Resources (Centro Ligure per le Risorse Biologiche) since 2006; Member of the Board, PhD Program in Biotechnology and Regenerative Medicine, University of Genova, since 2007

    Awards/Honors: Senior Achievement Award American Academy of Ophthalmology (2008); Silver Fellowship Association for Research in Vision and Ophthalmology (2009)

  • Paul L. Kaufman, MD, MD(HC)

    Affiliations: Wisconsin Regional Primate Research Center, Animal Health and Biomedical Sciences - School of Veterinary Medicine, Director-Glaucoma Services

    Research Interests: My research centers on studies of the physiology, pharmacology, morphology, cell biology, genetic manipulation, neural control, biomechanics and aging of the aqueous humor formation and drainage and accommodative mechanisms in the non-human primate, seeking to understand the pathophysiology and develop new therapies for the human diseases of glaucoma and presbyopia.

    Glaucoma is the second most common cause of irreversible visual loss in adult Americans, the most common among African Americans, and the most common world-wide, while presbyopia is the most common of all ocular afflictions.

  • David Broadway MD BSc(Hons) FRCOphth DO(RCS)

    Affiliation: Consultant Ophthalmic Surgeon at the Norfolk & Norwich University Hospital.
    Honorary Reader at the University of East Anglia UK. Trained at St Thomas’ Hospital, London, Moorfields Eye Hospital, London and the University of British Columbia, Vancouver.

    Research interest: Research, carried out at the London Institute of Ophthalmology, focused on trabeculectomy, wound healing and factors affecting the conjunctiva, particularly previous topical medication. At the University of East Anglia he is part of Dr Julie Sanderson’s team researching human retinal cell and organotypic cultures with respect to glaucoma neuroprotection. He has an interest in adherence with anti-glaucoma therapy and has been a co-investigator on several multicentre studies. At present he is working on the Norwich Adherence in Glaucoma Study (NAGS), the Norfolk EPIC Eye Study (epidemiology), the UK Glaucoma Treatment Study (UKGTS) and the Effectiveness in Angle-closure Glaucoma of Lens Extraction (EAGLE) Study.

    Leadership positions: Director of the Norwich Glaucoma Research Unit and Ophthalmology Directorate Research Lead at the Norfolk & Norwich University Hospital.

  • Tina Wong, BSc, MBBS, FRCOphth, FRCSEd, PhD

    Affiliation: Senior consultant, Singapore National Eye Centre, Head of Ocular Therapeutics and Drug Delivery Research Group, Singapore Eye Research Institute, adjunct faculty at School of Materials Science Engineering, Nanyang Technological University and National University Health System, Singapore.

    Areas of Interest: sustained drug delivery systems for ocular disease, ocular surface disease and glaucoma, cellular mechanisms of wound healing following medical and surgical treatment in glaucoma and holds several patents on sustained drug delivery systems, and a glaucoma surgical device. She has published widely in these areas of research, co-authored 3 book chapters and authored a book for patients on glaucoma.

    Leadership Position: co-Director of the Ocular Therapeutics and Engineering Centre at Nanyang Technological University, Chairman of Fundraising Singapore Eye Research Institute, Committee Member, Product Vigilance Advisory Committee of the Health Sciences Authority, Singapore, Ministry of Health, Clinician-scientist Residents, Scientific Advisory Board Scholarship Administration Panel Member.

    Honors: Distinguished Service Award Asia Pacific Academy of Ophthalmology, Singapore EXSA Clinical Service Award, Clinician Scientist Awardee, National Medical Research Council of Singapore, Physiological Society Award, Wellcome Trust Vision Research Fellowship awardee, recipient of the Oxford Congress Fould’s Trophy and Moorfields Research Medal.

  • Jeffrey Goldberg, MD, PhD

    Jeffrey Goldberg, MD, PhD, Professor and Director of Research

    Affiliation: Shiley Eye Center, University of California San Diego

    Research Interest: Neuroprotection and optic nerve regeneration; stem cells and nanotechnology

    Leadership positions: Director of Research, Shiley Eye Center

    Special Honors: Heed Foundation Fellowship (2009); Hope for Vision Scientist of the Year (2010); ARVO Cogan Award (2012); Cless Award (2013)

  • Christophe Baudouin, MD, PhD, FARVO

    Born in 1961, Christophe Baudouin is professor of Ophthalmology in Paris since 1995, after achieving is MD in Nice in 1989 and a PhD in Paris in 1992. Since 1995, he is also chairman of the department of Ophthalmology, Ambroise Paré Hospital, APHP, University of Versailles, and became in 2000 also the chairman of a large department of Ophthalmology in Quinze-Vingts National Ophthalmology Hospital, Paris. Since 2004 he is the Director of an INSERM-labelled research group, located in Vision Institute, University of Paris 6, a research center dedicated to ophthalmology and recently labelled as Laboratory of Excellence. He has been president of the Ophthalmological Society of Paris for 7 years. He is currently the Editor-in-chief of the French Journal of Ophthalmology, General Secretary of the French Society of Ophthalmology, vice-president of the French Glaucoma Society, and active member of eight international societies, including the prestigious American Ophthalmological Society. He was awarded in 2011 silver fellow of ARVO and is now part of the Academia Ophthalmologica Internationalis. He has published more than 250 papers in international peer-reviewed journals and has developed in his laboratory various original techniques and models, in particular flow cytometry or confocal microscopy in conjunctival imprints, in vivo confocal microscopy, as well as a large range of in vivo or in vitro models useful for toxicological or pathophysiological investigations.

  • KiHo Park, MD, PhD

    Affiliation: Professor of Ophthalmology, Seoul National University College of Medicine, Seoul National University Hospital, Seoul, Korea

    Areas of Interest: Disc Hemorrhage and Peripapillary Atrophy; Risk factors of Normal Tension Glaucoma; Early Detection of Glaucomatous Damage; Neuroprotection; Angle Closure Glaucoma

    Leadership Position: Steering Committee Member of WGA; Consensus and Guidelines Committee Member of WGA; WGC-2011 Scientific Program and Abstract Review Committee Member; WGC-2013 Program Committee Member; Executive member of Glaucoma Research Society; Board Member of Asia Pacific Glaucoma Society (APGC); Secretary General of Asian Angle-Closure Glaucoma Club (AACGC); Associate Editor of AACGC Textbook; Editor of Atlas of Angle Closure Glaucoma; Section Editor of Japanese Journal of Ophthalmology; Editorial Board of Asian Journal of Ophthalmology; Editorial Board of Korean Journal of Ophthalmology; Past Director of International Relation of Korean Ophthalmological Society; Past Director of Scientific Program of Korean Glaucoma Society

    Awards/Honors: Achievement Award from AAO; Distinguished Service Award from APAO; Taejoon Service Award from KOS; Topcon Ophthalmology Award; Jules Stein Eye Institute Laboratory Research Award; Yonahm Academy Award from Korean Glaucoma Society. Over 200 peer-reviewed publications and over 60 invited lectures at international meetings including WOC, WGC, APAO, SEAGIG, AACGC, AOGS, and APGC. Has served as a reviewer of more than 20 SCI journals

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