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OIC Part 1: Recommendations on Initiating Prescription Therapies for Opioid-Induced Constipation

Target Audience & Educational Design:
Recommendations on Initiating Prescription Therapies for Opioid-Induced Constipation enduring virtual seminars (webinars) are designed for clinicians and all healthcare practitioners involved in the treatment of patients in pain. This educational initiative was planned and facilitated by leaders and experts from the American Academy of Pain Medicine (AAPM). AAPM is the leading medical association representing physicians committed to advancing the emerging science and practice of pain medicine. This program is designed to improve access to quality, evidence-based multidisciplinary pain care across the healthcare continuum.

Purpose Statement:
The purpose of these enduring virtual seminars (webinars) is to discuss an optimal symptom-based method for assessing opioid-induced constipation in clinical practice and a threshold of symptom severity to prompt consideration of prescription therapy.

Educational Need:
OIC has evolved as an outcome of modern pain management techniques, with limited consensus on its treatment and its appropriate and concise definitions. Further, there is little evidence-based data to support best practice for treating OIC, and therefore a real need to define the problem and propose recommendations for treatment based upon the available evidence.

Educational Objectives for the Recommendations on Initiating Prescription Therapies for Opioid-Induced Constipation program are as follows:
- Define opioid-induced constipation.
- Identify selected factors to consider before evaluating patients’ potential need for OIC treatment using a validated assessment tool.
- Identify optimal treatment strategies for patients with OIC.
- Categorize various medication options to treat OIC.
- Match the mechanism to each drug class and medication discussed.

Fee Information& Refund/Cancellation Policy
There is no fee for this educational activity.

Accreditation:
The American Academy of Pain Medicine is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

Physician Credit Designation:
The American Academy of Pain Medicine designates this enduring material activity for a maximum of 1.25 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Pharmacist Accreditation Statement:
Global Education Group is accredited by the Accreditation Council for Pharmacy Education as a provider of continuing pharmacy education.

Credit Designation:
Global Education Group designates this continuing education activity for 1.25 contact hour (0.125 CEUs) of the Accreditation Council for Pharmacy Education. (Universal Activity Number - 0530-9999-16-047-H01-P)
This is a knowledge based activity.
 
Pharmacy learners will not be eligible to receive partial credit. Session must be attended in its entirety in order to receive credit for the 1.25 contact hour session. Notification of successful completion of courses will be communicated by Global Education Group to the ACPE CPE Monitor system, where all pharmacy learners’ credits are stored. Learner errors providing NABP numbers and/or DOB will result in unsuccessful reporting of credits to the CPE Monitor system. These credits will not be recorded. Ensuring records are accurate and complete will be the responsibility of the individual learner. For more information regarding CPE Monitor and issuance of ACPE credit, please visit: https://www.acpe-accredit.org/pharmacists/cpemonit...

Nursing Continuing Education:
Global Education Group is accredited as a provider of continuing nursing education by the American Nurses Credentialing Center’s COA.
This educational activity for 1.25 contact hours is provided by Global Education Group. Nurses should claim only the credit commensurate with the extent of their participation in the activity.

Global Contact Information
For information about the pharmacist or nursing accreditation of this program, please contact Global at 303-395-1782 or inquire@globaleducationgroup.com.

This activity is jointly provided by the American Academy of Pain Medicine and Global Education Group.



Term of Offering
This activity was released on April 21, 2016 and is valid for one year. Requests for credit must be made no later than April 21, 2017.

Disclosure of Unlabeled Use
This educational activity may contain discussion of published and/or investigational uses of agents that are not indicated by the FDA. Global Education Group (Global) and American Academy of Pain Medicine do not recommend the use of any agent outside of the labeled indications. The opinions expressed in the educational activity are those of the faculty and do not necessarily represent the views of any organization associated with this activity. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings.  

Disclaimer
Participants have an implied responsibility to use the newly acquired information to enhance patient outcomes and their own professional development. The information presented in this activity is not meant to serve as a guideline for patient management. Any procedures, medications, or other courses of diagnosis or treatment discussed in this activity should not be used by clinicians without evaluation of patient conditions and possible contraindications on dangers in use, review of any applicable manufacturer’s product information, and comparison with recommendations of other authorities.

Faculty/Planner Disclosure Policy Statement:
It is the policy of AAPM to plan and implement educational activities in accordance with ACCME’s Essential Areas and Elements to ensure balance, independence, objectivity, and scientific rigor. As an ACCME accredited provider, AAPM is eligible to receive commercial support from commercial interests but cannot receive guidance, either nuanced or direct, on the content of the activity or on who should deliver the content. All program faculty and planners are required to disclose all financial relationships they may have or have had within the last 12 months with commercial interests whose products or services are related to the subject matter of the presentation. Any real or apparent conflicts of interest will be resolved prior to the presentation. All confirmed faculty disclosure information will be made available to participants prior to the activity. Faculty will also be expected to disclose this information to the audience both verbally and in print (slide presentation) at the beginning of each presentation. Faculty members are also required to inform program participants if any unlabeled uses of products regulated by the U.S. Food and Drug Administration will be discussed.

Disclosures - Faculty Presenters:
Charles Argoff, MD, CPE
Professor of Neurology
Albany Medical College
Director
Comprehensive Pain Center
Albany Medical Center Department of Neurology
Albany, NY
Allergan (Honorarium, Speaker); AstraZeneca (Honorarium, Speaker/Consultant); Collegium (Honorarium, Consultant); Daiichi Sankyo (Honorarium, Consultant); Depomed (Honorarium, Speaker); Dong Therapeutics (Research Grant, Principal Investigator); Endo (Research Grant, Principal Investigator); Forest (Research Grant, Principal Investigator); Janssen (Honorarium, Speaker); Lilly (Research Grant, Principal Investigator); Pfizer (Honorarium, Consultant); Purdue (Honorarium, Consultant); Teva (Honorarium, Consultant); Xenoport (Honorarium, Speaker)

Michael Camilleri, MD, MPhil, MRCP, FACP, AGAF
Professor of Medicine, Pharmacology, and Physiology, Mayo Clinic College of Medicine
Consultant, Division of Gastroenterology and Hepatology, Mayo Clinic
Rochester, Minnesota
AstraZeneca (Research grant, Research study); Shionogi (Consulting fee, Advisory board); Takeda (No compensation, Advisory board.)

Jeffrey Fudin, PharmD, DAAPM, FCCP, FASHP
Adjunct Associate Professor
Western New England College of Pharmacy
Western New England University
Springfield, MA
Director
PGY2 Pharmacy Pain Residency
Samuel Stratton VA Medical Center, Pharmacy
Albany, NY
AstraZeneca (Honorarium, Speakers bureau/Advisory Board); Depomed (Honorarium, Advisory Board); Endo (Honorarium, Consultant); Kaleo (Honorarium, Speakers bureau/Advisory Board); Kem Pharm (Honorarium, Consultant); Millennium Health (Honorarium, Speakers Bureau/Advisory Board); Scilex Pharmaceuticals (Honorarium, Consultant.)

Brett Snodgrass, APRN, FNP-C
Family Nurse Practitioner
Director of Clinical Operations
LifeLinc Anesthesia, Memphis, TN
President, BBS Consultants, Olive Branch, MS
AstraZeneca (Honorarium, Speaker); Depomed Pharmaceuticals (Honorarium, Speaker); Iroko Pharmaceuticals (Honorarium, Speaker); McNeil (Honorarium, Speaker); Purdue Pharmaceuticals (Honorarium, Speaker.)
Financial support for this project was provided by educational grants from AstraZeneca Pharmaceuticals LP; Salix Pharmaceuticals, Inc.; Takeda Pharmaceuticals U.S.A., Inc., and Sucampo; and Shionogi Inc.
_______________________________________
Disclosures - Program Planners:
Charles Argoff, MD, CPE
Professor of Neurology
Albany Medical College
Director
Comprehensive Pain Center
Albany Medical Center Department of Neurology
Albany, NY
Allergan (Honorarium, Speaker); AstraZeneca (Honorarium, Speaker/Consultant); Collegium (Honorarium, Consultant); Daiichi Sankyo (Honorarium, Consultant); Depomed (Honorarium, Speaker); Dong Therapeutics (Research Grant, Principal Investigator); Endo (Research Grant, Principal Investigator); Forest (Research Grant, Principal Investigator); Janssen (Honorarium, Speaker); Lilly (Research Grant, Principal Investigator); Pfizer (Honorarium, Consultant); Purdue (Honorarium, Consultant); Teva (Honorarium, Consultant); Xenoport (Honorarium, Speaker)

Michael Camilleri, MD, MPhil, MRCP, FACP, AGAF
Professor of Medicine, Pharmacology, and Physiology, Mayo Clinic College of Medicine
Consultant, Division of Gastroenterology and Hepatology, Mayo Clinic
Rochester, Minnesota
AstraZeneca (Research grant, Research study); Shionogi (Consulting fee, Advisory Board); Takeda (No compensation, Advisory Board.)

Larry C. Driver, MD
Professor, Department of Pain Medicine,
Professor, Department of Critical Care
Division of Anesthesiology and Critical Care
The University of Texas MD Anderson Cancer Center
Houston, TX
Nothing to Disclose

Tracey O. Fremd, NP
Principal, Tracey Fremd Consulting, Inc.
Cameron Park, CA
Tracey Fremd Consulting (Salary, Principal/Consultant); Millennium Health (Honorarium, Speaker); Depomed (Honorarium; Speaker.)

Jeffrey Fudin, PharmD, DAAPM, FCCP, FASHP
Adjunct Associate Professor
Western New England College of Pharmacy
Western New England University
Springfield, MA
Director
PGY2 Pharmacy Pain Residency
Samuel Stratton VA Medical Center, Pharmacy
Albany, NY
AstraZeneca (Honorarium, Speakers bureau/Advisory Board); Depomed (Honorarium, Advisory Board); Endo (Honorarium, Consultant); Kaleo (Honorarium, Speakers bureau/Advisory Board); Kem Pharm (Honorarium, Consultant); Millennium Health (Honorarium, Speakers Bureau/Advisory Board); Scilex Pharmaceuticals (Honorarium, Consultant.)

Vitaly Gordin, MD
Associate Professor of Anesthesiology
Penn State University
Medical Director, Spine Center
Director, Pain Medicine Division
Penn State Hershey Medical Center
Hershey, PA
Nothing to Disclose

Rosemary Polomano, PhD, RN, FAAN
Professor of Pain Practice, Anesthesiology, and Critical Care
University of Pennsylvania School of Nursing
Philadelphia, PA
AcelEx (Honorarium-Consultant/Speaker); Mallinckrodt Pharmaceuticals (Honorarium-Speaker); Salix Pharmaceuticals (Honorarium-Speaker)

Brett Snodgrass, MSN, APRN, FNP-C
Family Nurse Practitioner
Director of Clinical Operations
LifeLinc Anesthesia, Memphis, TN
President, BBS Consultants, Olive Branch, MS
AstraZeneca (Honorarium, Speaker); Depomed Pharmaceuticals (Honorarium, Speaker); Iroko Pharmaceuticals (Honorarium, Speaker); McNeil (Honorarium, Speaker); Purdue Pharmaceuticals (Honorarium, Speaker.)

Lynn R. Webster, MD, FACPM, FASAM
Vice President, Scientific Affairs, PRA Health Sciences
Past President, American Academy of Pain Medicine
Salt Lake City, UT
AstraZeneca Pharmaceuticals (Consultant); Depomed (Advisory Board.)

Jennifer Westlund, MSW
Director of Education
American Academy of Pain Medicine
Chicago, IL
Nothing to disclose

Ashley Marostica, RN, MSN
Nothing to Disclose

Amanda Glazar, PhD
Nothing to Disclose

Laura Gilsdorf
Nothing to Disclose  
Financial Support:
Financial support for the Recommendations on Initiating Prescription Therapies for Opioid-Induced Constipation project was provided by educational grants from AstraZeneca Pharmaceuticals LP; Salix Pharmaceuticals, Inc.; Takeda Pharmaceuticals U.S.A., Inc., Sucampo and Shionogi Inc.


Endorsed by the AGA Institute
AAPM's Opioid-Induced Constipation on-demand education courses are endorsed by the American Gastroenterological Association (AGA) Institute

Instructions for Course Participants:

This enduring material activity will consist of a didactic presentation accompanied by PowerPoint slides. 
  • The learner is required to respond to the pre-assessment question(s) before beginning the presentation. Since it is not possible to fail a pre-test, upon submission, "passed" will appear on your screen. This is not an indication that questions were answered correctly.
  • While listening to/viewing content, you may pause the presentation at any time to record notes, etc., and re-start where you left off.
  • You are required to view the entire presentation.
  • Learners must answer all post-assessment questions and receive a passing score (minimum 70%) to proceed to the activity evaluation. Learners will be allowed a maximum of three opportunities to successfully receive a passing score.
  • An evaluation must be completed prior to receipt of your certificate.
  • After completing the post-test and activity evaluation(s), a statement of credit will be generated and printed on your own at your convenience.
For additional assistance, please contact the American Academy of Pain Medicine, 8735 W. Higgins Road, Suite 300, Chicago, IL 60631, 847-375-4731.

If you need further assistance with software requirements please contact, support@blueskybroadcast.com.

Internet CME Policy
In regard to its CME programming and initiatives, The American Academy of Pain Medicine is committed to protecting the privacy of its members and customers. AAPM maintains its Internet site as an information resource and service for physicians and other health care professionals. AAPM will ensure that all personal and credit card information be kept confidential when participating in any Internet CME activity and that personal information will not be shared with any person/entity outside of AAPM. AAPM will ask for only that information necessary to provide the service(s) requested.