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Neural Mechanisms of Painful TMJ Pathologies and Their Clinical Implications

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2021 IADR/AADR/CADR General Session

The 99th General Session & Exhibition of the IADR was to be held in conjunction with the 50th Annual Meeting of the American Association for Dental Research and the 45th Annual Meeting of the Canadian Association for Dental Research, from July 21-24, 2021 as a Virtual Experience.

The recordings in this library from the meeting are a selection of the science that was to be presented as part of the General Session. These recordings give you the opportunity to participate in the meeting and hear from leading researchers. The recordings include IADR Distinguished Lecture Series speakers, the IADR Academy and symposia from a collection of scientific groups and networks.

This session can be purchased as part of the full meeting recordings within the product bundles

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Session Description 
Temporomandibular disorder (TMD) is a collective symptoms characterized primarily by persistent pain and functional disturbances. Pain from the temporomandibular joint (TMJ) is a major symptom of TMD. Although various pathologies within TMJ such as inflammation or degeneration can contribute to the persistent pain, the therapeutic management of such conditions is often not effective and so it is necessary to develop novel mechanism-based approaches to effectively treat the persistent pain conditions. It is well known that TMD is multifactorial condition and both peripheral as well as central mechanisms are intricately involved. It is important to identify local and systemic factors that contribute to persistent pain. Endogenous pain modulatory system and sex differences in painful TMD are also an important factors. This symposium will outline recently identified novel findings of the neural, molecular and neuro-endocrinological mechanisms underlying TMJ pain in rodent models and their implications for diagnosis and novel management of TMD.

Learning Objectives
  • Attendees will understand the etiologies and symptoms of painful TMD pathologies and learn current animal models for studying painful TMD.
  • Attendees will be able to recognize local and systemic contributors to regulate the extent of pain from TMJ inflammation.
  • At the end of the symposium, attendees will appreciate the importance of developing novel clinical approaches with strong mechanistic basis for management of TMD.
Presentation Date
July 23, 2021

Barry Sessle
Feng Tao
Akimasa Tashiro
Yu Shin Kim

Sponsoring Groups/Networks
International Network for Orofacial Pain and Related Disorders Methodology, Neuroscience, Pharmacology/Therapeutics/Toxicology

CE Credits
1.5 Contact Hours

Financial Interest Disclosure:

Not eligible for individual purchase must purchase as part of a meeting bundle.