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Inflammation and Regeneration of the Dentin-pulp Complex

2021 IADR/AADR/CADR General Session

The 99th General Session & Exhibition of the IADR was to be held in conjunction with the 50th Annual Meeting of the American Association for Dental Research and the 45th Annual Meeting of the Canadian Association for Dental Research, from July 21-24, 2021 as a Virtual Experience.

The recordings in this library from the meeting are a selection of the science that was to be presented as part of the General Session. These recordings give you the opportunity to participate in the meeting and hear from leading researchers. The recordings include IADR Distinguished Lecture Series speakers, the IADR Academy and symposia from a collection of scientific groups and networks.

This session can be purchased as part of the full meeting recordings within the product bundles

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Session Description 
Inflammation and Regeneration are closely linked to each other and their significance in translational research is rapidly increasing. In the dental pulp, invading bacteria cause carious lesions due to the bacteria releasing toxins as well as competing for nutrients. The odontoblasts and the dental pulp cells are able to detect infection and release several pro-inflammatory mediators including increase in cytokines and chemokines which result in the recruitment of immune system cells to target the invading microbes. recent observations suggest that the local inflammation produced by injury and its timely resolution are both important for regeneration. The dental-pulp harbors a variety of cell-types which can mediate an innate immune response. Thus, the current treatment modality would be to develop anti-inflammatory and immunomodulatory approaches for regeneration of the dentin-pulp complex. Thus, both adaptive immunity with regenerative competence is required for dental pulp and dentin regeneration and repair.

Learning Objectives
  • Demonstrate the regenerative potential of the different types of adult stem cells.
  • Raise awareness for the role of complement factors.
  • Demonstrate opportunities of novel strategies for the regeneration of the dentin-pulp complex.
Presentation Date
July 22, 2021

Fionnuala Lundy
Imad About
Jennifer Gibbs
Paul Cooper

Sponsoring Groups/Networks
Mineralized Tissue, Stem Cell Biology Research

CE Credits
1.5 Contact Hours

Financial Interest Disclosure:

Not eligible for individual purchase must purchase as part of a meeting bundle.