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How to Rescue a pH Sensitive Protein: Detergent Viral Inactivation and Analytical Quantitation of Residual Detergent

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Contributors

  • Jessica Dawson, Ph.D.

    Jessica Dawson is the Associate Director for the Analytical Development group in Protein and Cell Sciences at EMD Serono. Her group supports the biological research pipeline by developing methods and performing biophysical and biochemical characterization of biotherapeutics, including antibodies and fusion molecules. Jessica was a key member of a multi-site initiative encompassing research, development, and manufacturing to streamline processes and create harmonized methods so biotherapeutics could progress seamlessly from research to the clinic. Jessica has worked at EMD Serono for eleven years. Prior to that she was a post-doc at the University of Pennsylvania studying structure function relationships on the EGFR family of receptors. Jessica received her B.S. from Rutgers University in New Jersey and her Ph.D. in Molecular Biophysics and Biochemistry from Yale University.

  • Corinne Miller, Ph.D.

    Dr. Corinne Miller, PhD, is the R&D Manager for Virology & Microbiological Sciences at MilliporeSigma.She has 20+ years’ experience in the Life Sciences and Bioprocessing industries.She currently leads an R&D team conducting bacterial and viral clearance characterization for sterilizing and virus filtration, virus inactivation technologies, microbial integrity testing for single-use and sterile connection and sampling technologies, bioburden assessment and sanitant efficacy studies for biotherapeutic processing applications.Her career began as a cellular & molecular biologist, developing chemiluminescent detection and assay technologies for DNA sequencing, nucleic acid and protein immunoblotting, ELISA, cell-based gene expression and influenza assay systems. She has worked on instrument platforms for high throughput imaging and array-based surface plasmon resonance. She earned a BS in Microbiology from the Pennsylvania State University, and a PhD in Cellular & Molecular Biology from the Massachusetts Institute of Technology.

September 20, 2018
Thu 12:30 PM EDT

Duration 1H 30M

This live web event has ended.