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Considerations for Development of Biologics in Combination Regimens: Risk Assessment for Immunogenicity and Bioanalytical Considerations

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Contributors

  • Alex Kozhich, Ph.D.

    Alex Kozhich has over 17 years of experience in the pharmaceutical industry. For the past 8 years, Alex has worked as a Senior Principal Scientist in the Bioanalytical Sciences Department at Bristol Myers Squibb. In this role, he provides bioanalytical support to large molecule discovery and development projects. Previously, Alex was an early discovery scientist at MedImmune, and also worked at a couple of smaller diagnostic companies. He has authored over 100 papers and/or poster presentations as primary or co-author and presented at scientific conferences across the United States, and his research interests include bioanalytical methods for biomolecules, peptide and protein biochemistry and immunology. Alex received his Ph.D. in Organic Chemistry from Shemyakin Institute of Bioorganic Chemistry and completed postdoctoral training in immunology at National Institutes of Health.

  • Jad Maamary, Ph.D.

    Jad Maamary is an Associate Principal Scientist at Merck. Jad is responsible for developing and implementing in silico and ex vivo platforms to assess the immunogenicity of various biologics. His current work investigates the interplay between immune modulators and cross-reactive T cell receptors that lead to breaking of immune tolerance.

    Prior to Joining Merck, Jad was a post-doctoral fellow at Rockefeller University working in Jeffrey Ravetch’s Lab. His Fellowship work investigated the role IgG-Fc modifications in fine tuning the immune response to infection and vaccination. Jad Maamary obtained his PhD in Molecular Virology under the mentorship of Peter Palese at the Mount Sinai School of Medicine where he designed and generated novel viral vaccine vectors and investigated their efficiency in eliciting potent immune responses.

March 6, 2019
Wed 12:30 PM EST

Duration 1H 30M

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