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Dr. Betts is a member of the Translational Modeling & Simulation Group in
the Biomedicine Design department at Pfizer, where she is
translational modeling and simulation (M&S) lead supporting the Oncology
Research Unit. In this role she leads a team responsible for using M&S
strategies to answer mechanistic questions, validate targets, select optimal
compounds, translate preclinical data to the clinic and predict efficacious
dose/regimen. Her main area of work is on novel biotherapeutic modalities
in immune-oncology including checkpoint inhibitor mAbs, bi-specific T-cell
retargeting molecules, targeted nanoparticles and drug conjugates for treatment
of cancer. Prior to these roles, Dr. Betts worked across many Research Units at
Pfizer (including Pain, Cardiovascular and Antibacterial) to establish modeling
and translational pharmacology to drive projects forward.